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Protein Overview: RXT2

General Information:
Name(s) found: RXT2 / YBR095C [SGD]
Description(s) found:
Found 16 descriptions.
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  • Subunit of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 453 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: negative regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    conjugation with cellular fusion [IMPLink to PubMed article]
    invasive growth in response to glucose limitation [IMPLink to PubMed article]
    histone deacetylation [IDALink to PubMed articleLink to PubMed article]
    Molecular Function: histone deacetylase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTASPAKKRL RNKYLSCCFL LIEMTIRSSM KNNAELESKS VLANESNIIS TFTRRIIKEK  60
   61 SGNYQVLKRS LDGKLIYPEA TGISSNRGNK LLQRSEVVTR RDLNNSKPMI EQTVFYNGSE 120
  121 HRLLQTNIVT DSRRKRIKFT PDINVEPVLV GDENDIDGSE KEDENITDEY YGEEDDDDLS 180
  181 KLVNVKEILT PILSLGDIIN HKTISRTFSS PILKNLALQI ILMIEKEQMS VVRYSQFLEV 240
  241 FLGDHPEPIY ESNLNLPSYN HNLTLPEDRG ASDEDDINNK NNINEVNSNS LSTEAGHINN 300
  301 GMEEFGEEDP FFALPRLEQS NALLSLLPSS SGSASISTLT AAEQQQLNEE IESARQLSQI 360
  361 ALQRNKEFIR NLQKIRKSVI KANRIRGRIL NWSREYLGIS DDDITIPVAL RVVKRGLISA 420
  421 TTNKTTNFEE EIENTMEDGV VDDNEPDEEA NRA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..453] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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