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Protein Overview: FAT1

General Information:
Name(s) found: FAT1 / YBR041W [SGD]
Description(s) found:
Found 9 descriptions.
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  • Very long chain fatty acyl-CoA synthetase and long chain fatty acid transporter; activates imported fatty acids with a preference for very long lengths (C20-C26); has a separate function in the transport of long chain fatty acids [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 623 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDALink to PubMed article]
    peroxisome [IDALink to PubMed article]
    microsome [IDALink to PubMed article]
    plasma membrane [IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: lipid transport [IMPLink to PubMed article][ISSLink to PubMed article]
    very long-chain fatty acid metabolic process [IMPLink to PubMed article]
    Molecular Function: long-chain fatty acid-CoA ligase activity [IMPLink to PubMed article][ISSLink to PubMed article]
    long-chain fatty acid transporter activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPIQVVVFA LSRIFLLLFR LIKLIITPIQ KSLGYLFGNY FDELDRKYRY KEDWYIIPYF  60
   61 LKSVFCYIID VRRHRFQNWY LFIKQVQQNG DHLAISYTRP MAEKGEFQLE TFTYIETYNI 120
  121 VLRLSHILHF DYNVQAGDYV AIDCTNKPLF VFLWLSLWNI GAIPAFLNYN TKGTPLVHSL 180
  181 KISNITQVFI DPDASNPIRE SEEEIKNALP DVKLNYLEEQ DLMHELLNSQ SPEFLQQDNV 240
  241 RTPLGLTDFK PSMLIYTSGT TGLPKSAIMS WRKSSVGCQV FGHVLHMTNE STVFTAMPLF 300
  301 HSTAALLGAC AILSHGGCLA LSHKFSASTF WKQVYLTGAT HIQYVGEVCR YLLHTPISKY 360
  361 EKMHKVKVAY GNGLRPDIWQ DFRKRFNIEV IGEFYAATEA PFATTTFQKG DFGIGACRNY 420
  421 GTIIQWFLSF QQTLVRMDPN DDSVIYRNSK GFCEVAPVGE PGEMLMRIFF PKKPETSFQG 480
  481 YLGNAKETKS KVVRDVFRRG DAWYRCGDLL KADEYGLWYF LDRMGDTFRW KSENVSTTEV 540
  541 EDQLTASNKE QYAQVLVVGI KVPKYEGRAG FAVIKLTDNS LDITAKTKLL NDSLSRLNLP 600
  601 SYAMPLFVKF VDEIKMTDNL IKF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..75]
    [99..112]
    [254..524]    		 PSI-BLAST 192.08661 Luciferase
    2 View Details [76..98]
    [113..253]
    [525..623]    		 PSI-BLAST 192.08661 Luciferase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.23

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle