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Protein Overview: CSG2

General Information:
Name(s) found: CSG2 / YBR036C [SGD]
Description(s) found:
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  • gi|976270|dbj|BAA05666.1| Cls2p (Ca2+-regulatory membrane protein) [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6319510|ref|NP_009592.1| Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; Csg2p [Saccharomyces cerevisiae] [NCBI NR]
  • pir||S45894 regulatory protein CSG2 precursor - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|536254|emb|CAA84978.1| CSG2 [Saccharomyces cerevisiae] [NCBI NR]
  • CSG2 Calcium dependent regulatory protein [mips]
  • Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations [SGD]
  • CSG2, Chr II from 309040-310272, reverse complement [yeast_orfs2]
  • Chr II from 309040-310272, reverse complement [yeastorf3.fasta]
  • Chr II from 310272-309040, reverse complement [yeastorf5.fasta]
  • CSG2 SGDID:S0000240, Chr II from 310275-309043, reverse complement, Verified ORF [yeastflysequest.fasta]
  • CSG2 SGDID:S0000240, Chr II from 310313-309081, reverse complement, Verified ORF [10112005cervSGD.fasta]
  • Csg2p [Saccharomyces cerevisiae]gi|536254|emb|CAA84978.1| CSG2 [Saccharomyces cerevisiae]gi|626869|pir||S45894 regulatory protein CSG2 precursor - yeast (Saccharomyces cerevisiae)gi|976270|dbj|BAA05666.1| Cls2p (Ca2+-regulatory membrane protein) [Sacch [nrdb_11152004_Chlamydomonas]
  • CSG2 SGDID:S000000240, Chr II from 310313-309081, reverse complement, Verified ORF, "Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; Csg2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Cls2p (Ca2+-regulatory membrane protein) [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • CSG2 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CSG2 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • CSG2 SGDID:S000000240, Chr II from 310313-309081, Genome Release 64-1-1, reverse complement, Verified ORF, "Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations" [yeast-030211-contam.fasta]
  • CSG2 SGDID:S000000240, Chr II from 310313-309081, Genome Release 64-2-1, reverse complement, Verified ORF, "Endoplasmic reticulum membrane protein; required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein abundance increases in response to DNA replication stress" [20141208_orf_trans.fasta]
  • YBR036C SGDID:S000000240, Chr II from 310313-309081, Genome Release 64-1-1, reverse complement, Verified ORF, "Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 410 amino acids

    Gene Ontology:
    Cellular Component: integral to endoplasmic reticulum membrane [IDALink to PubMed article]
    Biological Process: response to drug [IMPLink to PubMed article]
    glycosphingolipid biosynthetic process [ISSLink to PubMed article]
    cellular calcium ion homeostasis [IMPLink to PubMed article]
    Molecular Function: enzyme regulator activity [IMPLink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTLLWFSS VIGYVIQTKC LSNIQSKKEI SVGPNGTIAT PETNGDNGNS SSLTFYLTFM  60
   61 YFASWLLLVP ASRLWEKMRP MFVSDSDSNR NSQFDNNNSG SVTNEDVDTF SHVLDDPQPR 120
  121 IPAQQQKQKI ISVATFKYVA KLTVLALIMI VADLTYNMAL SLSPAFDVAL MQNTAIFEIV 180
  181 TLLYGVCGIS RKNYVFRNFL IMMNAVIGIL IISYTKATCD MLAGKLSVNP NTGELSDPFL 240
  241 FDRLKGALIC GLGALIMGPF AVLWNRWFCS NISKNENSAV VLVKQSTHMA LIGIIGMVIL 300
  301 LPFIPKFPSR ESVESISLFY NDKSFWFSLL GSIIFGSLPS LISILELNRK APAEYLTTCN 360
  361 LGAIIFMGLA EWVCEPTQTT IVRWEVIGYI MLTVSLLVLS VTLGEGKYHH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CSG2 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] MSA 1.002958 View MSA. No confident structure predictions are available.
    2 View Details [97..410] deduced N/A No confident structure predictions are available.
    3 View Details [271..410] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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