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Protein Overview: COQ1

General Information:
Name(s) found: COQ1 / YBR003W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 473 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article][IMPLink to PubMed article]
    Biological Process: ubiquinone biosynthetic process [IMPLink to PubMed article]
    Molecular Function: trans-hexaprenyltranstransferase activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQRSGAAHH IKLISSRRCR FKSSFAVALN AASKLVTPKI LWNNPISLVS KEMNTLAKNI  60
   61 VALIGSGHPV LNKVTSYYFE TEGKKVRPLL VLLLSRALSE IPMTERNHLK IDKSDVPEDP 120
  121 IYSKPSQNQL FQRPASSISP LHILHGIKPL NPLTKGPEPL PEETFDKQRG ILPKQRRLAE 180
  181 IVEMIHTASL LHDDVIDHSD TRRGRPSGNA AFTNKMAVLA GDFLLGRATV SISRLHNPEV 240
  241 VELMSNSIAN LVEGEFMQLK NTSIDADIDT IENGHKLLPV PSKKLEVKEH DFRVPSRQQG 300
  301 LQLSHDQIIE TAFEYYIHKT YLKTAALISK SCRCAAILSG ASPAVIDECY DFGRNLGICF 360
  361 QLVDDMLDFT VSGKDLGKPS GADLKLGIAT APVLFAWKED PSLGPLISRN FSERGDVEKT 420
  421 IDSVRLHNGI AKTKILAEEY RDKALQNLRD SLPESDARSA LEFLTNSILT RRK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data COQ1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] deduced N/A No confident structure predictions are available.
    2 View Details [102..295]
    [321..346]    		 PSI-BLAST 67.39794 Farnesyl diphosphate synthase
    3 View Details [296..320]
    [347..473]    		 PSI-BLAST 67.39794 Farnesyl diphosphate synthase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.49

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle