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Protein Overview: RER2

General Information:
Name(s) found: RER2 / YBR002C [SGD]
Description(s) found:
Found 36 descriptions.
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  • Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 286 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDALink to PubMed articleLink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [IMPLink to PubMed article]
    dolichol biosynthetic process [IDALink to PubMed article]
    protein amino acid glycosylation [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: prenyltransferase activity [IDALink to PubMed articleLink to PubMed article]
    dehydrodolichyl diphosphate synthase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METDSGIPGH SFVLKWTKNI FSRTLRASNC VPRHVGFIMD GNRRFARKKE MDVKEGHEAG  60
   61 FVSMSRILEL CYEAGVDTAT VFAFSIENFK RSSREVESLM TLARERIRQI TERGELACKY 120
  121 GVRIKIIGDL SLLDKSLLED VRVAVETTKN NKRATLNICF PYTGREEILH AMKETIVQHK 180
  181 KGAAIDESTL ESHLYTAGVP PLDLLIRTSG VSRLSDFLIW QASSKGVRIE LLDCLWPEFG 240
  241 PIRMAWILLK FSFHKSFLNK EYRLEEGDYD EETNGDPIDL KEKKLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen MDM1 RER2 1 Unpublished Fields Lab Data
    View Screen NAF1 RER2 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RER2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..286] PSI-BLAST 359.035458 Undecaprenyl diphosphate synthase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • prenyltransferase activity
    		•  4.40397054534951 bayes_pls_golite062009
  • di-trans,poly-cis-decaprenylcistransferase activity
    		•  3.07573514495519 bayes_pls_golite062009
  • transferase activity
    		•  1.42376896518855 bayes_pls_golite062009
  • catalytic activity
    		•  0.878978773660153 bayes_pls_golite062009
  • dehydrodolichyl diphosphate synthase activity
    		•  0.761527128946352 bayes_pls_golite062009
  • binding
    		•  0.747530931796963 bayes_pls_golite062009
  • protein binding
    		•  0.746384987072271 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  0.256467886977999 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle