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Protein Overview: AI5_ALPHA

General Information:
Name(s) found: AI5_ALPHA / Q0070 [SGD]
Description(s) found:
Found 22 descriptions.
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  • Endonuclease I-SceIV, involved in intron mobility; encoded by a mobile group I intron within the mitochondrial COX1 gene [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 630 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [TASLink to PubMed article]
    Biological Process: movement of group I intron [IMPLink to PubMed article]
    Molecular Function: endonuclease activity [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG NSQLFNVLVV  60
   61 GHAVLMIFFL VMPALIGGFG NYLLPLMIGA TDTAFPRINN IAFWVLPMGL VCLVTSTLVE 120
  121 SGAGTGWTVY PPLSSIQAHS GPSVDLAIFA LHLTSISSLL GAINFIVTTL NMRTNGMTMH 180
  181 KLPLFVWSIF ITAFLLLLSL PVLSAGITML LLDRNFNTSF FEVSGGGDPI LYEHLFWFFG 240
  241 HPEVYILIIP GFGIISHVVS TYSKKPVFGE ISMVYAMASI GLLGFLVWSH HMYIVGLDAD 300
  301 TRAYFTSATM IIAIPTGIKI FSWLMNPFSK DKNKNKNKKL IRNYQKMNNN NMMKTYLNNN 360
  361 NMIMMNMYKG NLYDIYPRSN RNYIQPNNIN KELVVYGYNL ESCVGMPTYT NIVKHMVGIP 420
  421 NNILYIMTGI LLTDGWIDYT SKKDLDKKTI MEINCRFRLK QSMIHSEYLM YVFMLLSHYC 480
  481 MSYPKMKIAK VKGKSYNQLE FYTRSLPCFT ILRYMFYNGR VKIVPNNLYD LLNYESLAHM 540
  541 IMCDGSFVKG GGLYLNLQSF TTKELIFIMN ILKIKFNLNC TLHKSRNKYT IYMRVESVKR 600
  601 LFPMIYKYIL PSMRYKFDIM LWQKKYNMIN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AI1 AI4 AI5_ALPHA SCEI

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..515] PSI-BLAST 165.0 Mitochondrial cytochrome c oxidase, subunit I
    2 View Details [516..630] PSI-BLAST 29.69897 The homing endonuclease I-SceI bound to its DNA recognition region


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle