YRC Public Data Repository - Protein Structure Prediction

Protein:	AI5_ALPHA
Organism:	Saccharomyces cerevisiae
Length:	630 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AI5_ALPHA.

Description	E-value	Query Range	Subject Range
gi\|55975988 - gi\|55975988\|gb\|AAV68252.1\| cytochrome oxidase subunit 1-2 [Daucus carota]	617.0	[0..2]	[535..4]
gi\|108598208 - gi\|108598208\|gb\|ABF93413.1\| cytochrome c oxidase subunit I [Simulium bidentatum]	610.0	[0..2]	[515..2]
gi\|108598273 - gi\|108598273\|gb\|ABF93416.1\| cytochrome c oxidase subunit I [Simulium rufibasis]	608.0	[0..2]	[515..2]
gi\|16265496 - gi\|16265496\|gb\|AAL16493.1\| cytochrome c oxidase subunit I [Hypseleotris klunzingeri]	607.0	[0..2]	[518..2]
gi\|108598257 - gi\|108598257\|gb\|ABF93415.1\| cytochrome c oxidase subunit I [Simulium quinquestriatum]	607.0	[0..2]	[515..2]
gi\|111183085, gi... - pir\|\|T09801 cytochrome-c oxidase (EC 1.9.3.1) chain I - African malaria mosquito mitochondrion (frag... AGAP028364-PA - Cytochrome c oxidase subunit 1 \|protein_coding\|Mt:1424-2960:1\|gene:AGAP028364 gi\|111183097 - gi\|111183097\|gb\|ABH07865.1\| cytochrome oxidase subunit I [Anopheles quadriannulatus] gi\|111183091, gi... - gi\|111183094\|gb\|ABH07863.1\| cytochrome oxidase subunit I [Anopheles melas], gi\|111183091\|gb\|ABH07861... gi\|111183082 - gi\|111183082\|gb\|ABH07855.1\| cytochrome oxidase subunit I [Anopheles arabiensis]	605.0	[0..3]	[518..2]
gi\|87083517 - gi\|87083517\|gb\|ABD19215.1\| cytochrome oxidase subunit 1 [Daphnia pulex]	604.0	[0..1]	[515..1]

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Predicted Domain #1

Region A:
Residues: [1-515]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQRWLYSTN AKDIAVLYFM LAIFSGMAGT AMSLIIRLEL AAPGSQYLHG NSQLFNVLVV  60
   61 GHAVLMIFFL VMPALIGGFG NYLLPLMIGA TDTAFPRINN IAFWVLPMGL VCLVTSTLVE 120
  121 SGAGTGWTVY PPLSSIQAHS GPSVDLAIFA LHLTSISSLL GAINFIVTTL NMRTNGMTMH 180
  181 KLPLFVWSIF ITAFLLLLSL PVLSAGITML LLDRNFNTSF FEVSGGGDPI LYEHLFWFFG 240
  241 HPEVYILIIP GFGIISHVVS TYSKKPVFGE ISMVYAMASI GLLGFLVWSH HMYIVGLDAD 300
  301 TRAYFTSATM IIAIPTGIKI FSWLMNPFSK DKNKNKNKKL IRNYQKMNNN NMMKTYLNNN 360
  361 NMIMMNMYKG NLYDIYPRSN RNYIQPNNIN KELVVYGYNL ESCVGMPTYT NIVKHMVGIP 420
  421 NNILYIMTGI LLTDGWIDYT SKKDLDKKTI MEINCRFRLK QSMIHSEYLM YVFMLLSHYC 480
  481 MSYPKMKIAK VKGKSYNQLE FYTRSLPCFT ILRYM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	165.0
Match:	1occA
Description:	Mitochondrial cytochrome c oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [516-630]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FYNGRVKIVP NNLYDLLNYE SLAHMIMCDG SFVKGGGLYL NLQSFTTKEL IFIMNILKIK  60
   61 FNLNCTLHKS RNKYTIYMRV ESVKRLFPMI YKYILPSMRY KFDIMLWQKK YNMIN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.69897
Match:	1r7mA
Description:	The homing endonuclease I-SceI bound to its DNA recognition region
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits