Protein Overview: KDM2A_MOUSE

General Information:
Name(s) found:	KDM2A_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|90111073\|sp\|P59997.2\|KDM2A_MOUSE RecName: Full=Lysine-specific demethylase 2A; AltName: Full=JmjC domain-containing histone demethylation protein 1A; AltName: Full=[Histone-H3]-lysine-36 demethylase 1A; AltName: Full=F-box and leucine-rich repeat prote [NCBI NR] Lysine-specific demethylase 2A OS=Mus musculus GN=Kdm2a PE=1 SV=2 [Swiss-Prot] JmjC domain-containing histone demethylation protein 1A OS=Mus musculus GN=Fbxl11 PE=1 SV=2 [Swiss-Prot] Tax_Id=10090 Splice Isoform 1 of JmjC domain-containing histone demethylation protein 1A [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] JmjC domain-containing histone demethylation protein 1A ([Histone-H3]-lysine-36 demethylase 1A) (F-box and leucine-rich repeat protein 11) (F-box/LRR-repeat protein 11) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Fbxl11 Isoform 1 of JmjC domain-containing histone demethylation protein 1A [mouse-ipi-250309-contam.fasta] JmjC domain-containing histone demethylation protein 1A ([Histone-H3]-lysine-36 demethylase 1A) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) [nr-271106-contam.fasta] IPI:IPI00742275.1\|SWISS-PROT:P59997-1\|ENSEMBL:ENSMUSP00000076698;ENSMUSP00000112270\|REFSEQ:NP_001001984 Tax_Id=10090 Gene_Symbol=Fbxl11 Isoform 1 of JmjC domain-containing histone demethylation protein 1A [ipi.MOUSE.fasta.20090209] Isoform 1 of Lysine-specific demethylase 2A OS=Mus musculus GN=Kdm2a [011711_HMR.fasta] Tax_Id=10090 Gene_Symbol=Kdm2a Isoform 1 of Lysine-specific demethylase 2A [EBI-IPI_mouse_2_08-18-2011_reversed.fasta] sp\|P59997\|KDM2A_MOUSE Lysine-specific demethylase 2A OS=Mus musculus GN=Kdm2a PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	1161 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] cellular_component [ND]
Biological Process:	chromatin modification [IEA] biological_process [ND] transcription [IEA] oxidation reduction [IEA] regulation of transcription [IEA]
Molecular Function:	DNA binding [IEA] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA] zinc ion binding [IEA] protein binding [IEA] oxidoreductase activity [IEA] metal ion binding [IEA] molecular_function [ND] histone demethylase activity (H3-K36 specific) [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPEEERIRY SQRLRGTMRR RYEDDGISDD EIEGKRTFDL EEKLQTNKYN ANFVTFMEGK  60
   61 DFNVEYIQRG GLRDPLIFKN SDGLGIKMPD PDFTVNDVKM CVGSRRMVDV MDVNTQKGIE 120
  121 MTMAQWTRYY ETPEEEREKL YNVISLEFSH TRLENMVQWP STVDFIDWVD NMWPRHLKES 180
  181 QTESTNAILE MQYPKVQKYC LISVRGCYTD FHVDFGGTSV WYHIHQGGKV FWLIPPTAHN 240
  241 LELYENWLLS GKQGDIFLGD RVSDCQRIEL KQGYTFVIPS GWIHAVYTPT DTLVFGGNFL 300
  301 HSFNIPMQLK IYSIEDRTRV PNKFRYPFYY EMCWYVLERY VYCITNRSHL TKDFQKESLS 360
  361 MDMELNELES GNGDEEGVDR EARRMNNKRS VLTSPVANGV NLDYDGLGKA CRSLPSLKKT 420
  421 LSGDSSSDST RGSHNGQVWD PQCSPKKDRQ VHLTHFELEG LRCLVDKLES LPLHKKCVPT 480
  481 GIEDEDALIA DVKILLEELA SSDPKLALTG VPIVQWPKRD KLKFPTRPKV RVPTIPITKP 540
  541 HTMKPAPRLT PVRPAAASPI VSGARRRRVR CRKCKACVQG ECGVCHYCRD MKKFGGPGRM 600
  601 KQSCVLRQCL APRLPHSVTC SLCGEVDQNE ETQDFEKKLM ECCICNEIVH PGCLQMDGEG 660
  661 LLNEELPNCW ECPKCYQEDS SDKAQKRKIE ESDEEAVQAK VLRPLRSCEE PLTPPPHSPT 720
  721 SMLQLIHDPV SPRGMVTRSS PGAGPSDHHS ASRDERFKRR QLLRLQATER TMVREKENNP 780
  781 SGKKELSEVE KAKIRGSYLT VTLQRPTKEL HGTSIVPKLQ AITASSANLR PNPRVLMQHC 840
  841 PARNPQHGDE EGLGGEEEEE EEEEEDDSAE EGGAARLNGR GSWAQDGDES WMQREVWMSV 900
  901 FRYLSRKELC ECMRVCKTWY KWCCDKRLWT KIDLSRCKAI VPQALSGIIK RQPVSLDLSW 960
  961 TNISKKQLTW LVNRLPGLKD LLLAGCSWSA VSALSTSSCP LLRTLDLRWA VGIKDPQIRD1020
 1021 LLTPPTDKPG QDNRSKLRNM TDFRLAGLDI TDATLRLIIR HMPLLSRLDL SHCSHLTDQS1080
 1081 SNLLTAVGSS TRYSLTELNM AGCNKLTDQT LFFLRRIANV TLIDLRGCKQ ITRKACEHFI1140
 1141 SDLSINSLYC LSDEKLIQKI S

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: KDM2A_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: