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Protein Overview: CG15539-PA

General Information:
Name(s) found: CG15539-PA / FBpp0085017 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG15539 (CG15539, FBgn0039782). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:26331709..26333702. It has the cytological map location 99F6. Based on sequence similarity, it is predicted to have molecular function</span>: procollagen-proline 4-dioxygenase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: peptidyl-proline hydroxylation to 4-hydroxy-L-proline. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 386 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IEA]
    procollagen-proline 4-dioxygenase complex [IC]
    Biological Process: oxidation reduction [IEA]
    peptidyl-proline hydroxylation to 4-hydroxy-L-proline [ISS]
    Molecular Function: procollagen-proline 4-dioxygenase activity [ISS]
    L-ascorbic acid binding [IEA]
    oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA]
    iron ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTLKDVEEA IRGLRLIQWT YSLPTAEMAK GVLQDIHHNT SLDGMQCITI ARHMVNYKDF  60
   61 IRAKEWLMVG LKMYEADEEI EYIYSQLGMP LVDFYELFVE IQDELGSRYL AMSELQLAIK 120
  121 NWPEKVSLQR ALSRLKMNIR IGKEPAEKKN KSKRVYKKCC SSECRPTAKL YCLYKTTSSY 180
  181 FLRLAPLKME LLSLDPYMVL FHDVVSDKDI VSIRNLTKGK LARTVTVSKD GNYTEDPDRT 240
  241 TKGTWLVENN ALIQRLSQLT QDMTNFDIHD ADPFQVLNYG IGGFYGIHFD FLEDAELDNF 300
  301 SDRIATAVFY LSDVPQGGAT IFPKLGLSVF PKKGSALLWY NLDHKGDGDN RTAHSACPTV 360
  361 VGSRWVMTKW INEREQIFRR PCLTSI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..173] PSI-BLAST 15.09691 Designed protein cTPR3
    2 View Details [174..386] PSI-BLAST 10.69897 No description for 2hbtA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle