Protein Overview: LAG3_RAT

General Information:
Name(s) found:	LAG3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|91982956\|gb\|ABE68618.1\| lymphocyte-activated gene 3 [Rattus norvegicus] [NCBI NR] gi\|81909483\|sp\|Q5BK54.1\|LAG3_RAT RecName: Full=Lymphocyte activation gene 3 protein; Short=LAG-3; AltName: CD_antigen=CD223; Flags: Precursor [NCBI NR] gi\|61889117\|ref\|NP_997678.2\| lymphocyte-activation gene 3 [Rattus norvegicus] [NCBI NR] gi\|60551428\|gb\|AAH91201.1\| Lymphocyte-activation gene 3 [Rattus norvegicus] [NCBI NR] gi\|149049456\|gb\|EDM01910.1\| lymphocyte-activation gene 3 [Rattus norvegicus] [NCBI NR] Lymphocyte activation gene 3 protein OS=Rattus norvegicus GN=Lag3 PE=2 SV=1 [Swiss-Prot] Tax_Id=10116 Lymphocyte-activation gene 3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Hypothetical protein [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] lymphocyte-activation gene 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Lymphocyte-activation gene 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] lymphocyte-activated gene 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Lag3 Lymphocyte activation gene 3 protein [rat-ipi-250309-contam.fasta] lymphocyte-activation gene 3 precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Lymphocyte activation gene 3 protein OS=Rattus norvegicus GN=Lag3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	525 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] external side of plasma membrane [UNKNOWN][IEA] integral to membrane [IEA]
Biological Process:	negative regulation of interleukin-2 biosynthetic process [UNKNOWN][IEA] cell surface receptor linked signaling pathway [UNKNOWN][IEA] negative regulation of T cell activation [UNKNOWN][IEA] positive regulation of natural killer cell mediated cytotoxicity [UNKNOWN][IEA]
Molecular Function:	transmembrane receptor activity [UNKNOWN][IEA] MHC class II protein binding [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQDLFLDLL LLQLLWEAPV VSSGPGKELS VVWAQEGAPV HLPCSLEFPH LDPNFLRRGW  60
   61 VTWQHRPDSD QPASIPALDL LQGMPSTRRH PPHRYTVLSV APGGLRSGRQ PLLSHVQLEK 120
  121 RGPQRGDFSL WLRPATRKDA GEYHAFVRLP DRDFSCSLRL RVGQASMIAS PPGTLKPSDW 180
  181 VILNCSFSRP DRPVSVHWFQ GQSRVPVHNS PRHYLAESFL LLPQVSPLDS GTWGCVLTYR 240
  241 DGFNVSITYN LKVQGLEPVA PLTVYAAEGS RVELPCHLPP VVGTPSLLIA KWTPPGGGPE 300
  301 LPVTGKSGNF TLQLENVGRA QAGTYTCSIH LQGRQLSAAV TLAVITVTPK SFGLPGSPQK 360
  361 LLCEVVPASG EGRFVWRPLS DLSRSSLGPV LELQEAKLLA EQWQCQLYEG QKLLGATVYT 420
  421 AESSSGAWSA KRISGDLKGG HLFLSLILGA LALFLLVTGA FGFHLWRRQL LRRRFSALEH 480
  481 GIRPPPVQSK IEELEREPET EMEPETEPDP EPQPEPELEP ESRQL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: LAG3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: