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Protein Overview: gi|62484308, gi|...

General Information:
Name(s) found: gi|62484308 [NCBI NR]
gi|61679363 [NCBI NR]
Description(s) found:
Found 3 descriptions.
SHOW ALL
  • gi|62484308|ref|NP_650878.3| CG5077, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|61679363|gb|AAG22160.2| CG5077, isoform A [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 816 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: steroid metabolic process [IEA]
    Molecular Function: oxysterol binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLLQRIANW ASDNRDGNVA DKATADAAKL NRKESYKAQR KNYRREKKRV ASELMNSLQD  60
   61 PAVIVLADWL KVRGTLKSWT KLWCVLKPGL LLIYKSQKTK SSHWVGTVML TSCQVIERPS 120
  121 KKDGFCFKLF HPLEQSIWAP RGPDKETIGA VVQPLPTAYL IFRAPSQAAG KCWMDALELS 180
  181 LRCSALLLRS NSSTGTAPTS SYIGEPLPVS HETQWSEADY EKHFNDHDLD ADSQNEAPNA 240
  241 VMSGLESESE SDPAEPAQDD VVDQQCVETS YVPFTEEEFG EQGEQVEELA EENKSLIWCI 300
  301 VKQVRPGMDL SKVVLPTFIL EPRSFLDKLS DSYYHADLLS KAVQEDDAFT RMKLVVQWYL 360
  361 SSFYKKPKGL KKPYNPILGE RFRCYWQHPS GSRTFYIAEQ VSHHPPVSAF YVTNREDGFS 420
  421 ITCSILAKSK FYGNSTSAVL EGAATMTLLP RGECYTATTP YAHCKGILMG TLSMELGGKI 480
  481 NIECENTGYR TELEFKLKPF LGGADATNVV VGKIKLGKET LATINGHWDK ECRVKDSKTG 540
  541 EETVLFKVDA ETRSKRLTRY MVPLDLQEAN ESQRLWQRVS EAIANEDQVA ATEEKTVLEE 600
  601 RQRADAKERL SSDSVHMPDL FELDSYGQWL YKYADLRPWD SRNDVRQYEC QFKVLTQTRH 660
  661 KSVPIVHGAE MIHPLRSSIE TLSRTQRQSP AGQPLPPGGS AVPKAKNKSL VLAPRDTNSD 720
  721 SSQSPQGAVK RSSSSAIKQL ALAVDQVNRV LEQHTRQLNE ISQRLERMQY SPPPSSMSAH 780
  781 SLHMLGGGVS QSTVIKSLIY ALIGLAFSLI LRWLFK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] PSI-BLAST 17.522879 Solution Structure of the Pleckstrin Homology Domain of Oxysterol-Binding Protein-Related Protein 8 (KIAA1451 Protein)
    2 View Details [203..272] deduced N/A No confident structure predictions are available.
    3 View Details [273..644] PSI-BLAST 74.0 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
    4 View Details [645..816] MSA 1.174978 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.71153495886736 bayes_pls_golite062009
  • protein binding
    		•  1.18328783605179 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
  • oxysterol binding
    		•  1.1738554488982 bayes_pls_golite062009
  • binding
    		•  0.958372296392311 bayes_pls_golite062009
    		• 0.35288515581255 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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