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Protein Overview: loqs-PC

General Information:
Name(s) found: loqs-PC / FBpp0099590 [FlyBase]
Description(s) found:
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  • gi|85724940|ref|NP_001033903.1| loquacious, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|84795302|gb|ABC65897.1| loquacious, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|63376297|gb|AAY40789.1| loquacious [Drosophila melanogaster] [NCBI NR]
  • The gene loquacious is referred to in FlyBase by the symbol Dmel\loqs (CG6866, FBgn0032515). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:13382648..13385674. It has the cytological map location 34B9. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; germ-line stem cell maintenance; pre-microRNA processing; female germ-line stem cell division. 16 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; anatomical structure; germarium; female germline cyst; nervous system; multi-cell-component structure; female reproductive system; embryonic nervous system; cytoplasmic part; external compound sense organ; commissure. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • type=protein; loc=2L:join(13382940..13383664,13383737..13384022,13384527..13384667); ID=FBpp0099590; name=loqs-PC; parent=FBgn0032515,FBtr0100220; dbxref=FlyBase_Annotation_IDs:CG6866-PC,FlyBase:FBpp0099590,GB_protein:ABC65897.1,REFSEQ:NP_001033903,GB_pro [fly-100309-contam.fasta]
  • loquacious [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG6866-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • loquacious CG6866-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:join(13382940..13383664,13383737..13384022,13384527..13384667); ID=FBpp0099590; name=loqs-PC; parent=FBgn0032515,FBtr0100220; dbxref=FlyBase_Annotation_IDs:CG6866-PC,FlyBase:FBpp0099590,GB_protein:ABC65897.1,REFSEQ:NP_001033903,GB_protein:ABC65897; MD5=f45a77e37d6653ad83f7b2339fa40a14; length=383; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(13382940..13383664,13383737..13384022,13384527..13384667); ID=FBpp0099590; name=loqs-PC; parent=FBgn0032515,FBtr0100220; dbxref=FlyBase_Annotation_IDs:CG6866-PC,FlyBase:FBpp0099590,GB_protein:ABC65897.1,REFSEQ:NP_001033903,GB_protein:ABC65897; MD5=f45a77e37d6653ad83f7b2339fa40a14; length=383; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Loquacious OS=Drosophila melanogaster GN=loqs PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:join(13382940..13383664,13383737..13384022,13384527..13384667); ID=FBpp0099590; name=loqs-PC; parent=FBgn0032515,FBtr0100220; dbxref=FlyBase_Annotation_IDs:CG6866-PC,FlyBase:FBpp0099590,GB_protein:ABC65897.1,REFSEQ:NP_001033903,GB_protein:ABC65897,FlyMine:FBpp0099590,modMine:FBpp0099590; MD5=f45a77e37d6653ad83f7b2339fa40a14; length=383; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • Loquacious OS=Drosophila melanogaster GN=loqs PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2L:join(13382940..13383664,13383737..13384022,13384527..13384667); ID=FBpp0099590; name=loqs-PC; parent=FBgn0032515,FBtr0100220; dbxref=FlyBase_Annotation_IDs:CG6866-PC,FlyBase:FBpp0099590,GB_protein:ABC65897.1,REFSEQ:NP_001033903,GB_protein:ABC65897,FlyMine:FBpp0099590,modMine:FBpp0099590; MD5=f45a77e37d6653ad83f7b2339fa40a14; length=383; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(13382940..13383664,13383737..13384022,13384527..13384667); ID=FBpp0099590; name=loqs-PC; parent=FBgn0032515,FBtr0100220; dbxref=FlyBase_Annotation_IDs:CG6866-PC,FlyBase:FBpp0099590,GB_protein:ABC65897.1,REFSEQ:NP_001033903,GB_protein:ABC65897,FlyMine:FBpp0099590,modMine:FBpp0099590; MD5=f45a77e37d6653ad83f7b2339fa40a14; length=383; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VJY9, Loquacious OS=Drosophila melanogaster GN=loqs PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0099590 type=protein; loc=2L:join(13382940..13383664,13383737..13384022,13384527..13384667); ID=FBpp0099590; name=loqs-PC; parent=FBgn0032515,FBtr0100220; dbxref=FlyBase_Annotation_IDs:CG6866-PC,FlyBase:FBpp0099590,GB_protein:ABC65897.1,REFSEQ:NP_001033903,GB_protein:ABC65897,FlyMine:FBpp0099590,modMine:FBpp0099590; MD5=f45a77e37d6653ad83f7b2339fa40a14; length=383; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:join(13382940..13383664,13383737..13384022,13384527..13384667); ID=FBpp0099590; name=loqs-PC; parent=FBgn0032515,FBtr0100220; dbxref=FlyBase_Annotation_IDs:CG6866-PC,FlyBase:FBpp0099590,GB_protein:ABC65897.1,REFSEQ:NP_001033903,GB_protein:ABC65897,UniProt/TrEMBL:Q4TZM6,FlyMine:FBpp0099590,modMine:FBpp0099590; MD5=f45a77e37d6653ad83f7b2339fa40a14; length=383; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 383 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    Biological Process: female germ-line stem cell division [IMP]
    central nervous system development [IMP]
    pre-microRNA processing [IDA][IMP]
    germ-line stem cell maintenance [IMP]
    Molecular Function: protein binding [IPI]
    double-stranded RNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQENFHGSS LPQQLQNLHI QPQQASPNPV QTGFAPRRHY NNLVGLGNGN AVSGSPVKGA  60
   61 PLGQRHVKLK KEKISAQVAQ LSQPGQLQLS DVGDPALAGG SGLQGGVGLM GVILPSDEAL 120
  121 KFVSETDANG LAMKTPVSIL QELLSRRGIT PGYELVQIEG AIHEPTFRFR VSFKDKDTPF 180
  181 TAMGAGRSKK EAKHAAARAL IDKLIGAQLP ESPSSSAGPS VTGLTVAGSG GDGNANATGG 240
  241 GDASDKTVGN PIGWLQEMCM QRRWPPPSYE TETEVGLPHE RLFTIACSIL NYREMGKGKS 300
  301 KKIAKRLAAH RMWMRLQETP IDSGKISDSI CGELEGENES VKHLFHTKVI CFNSPLACVI 360
  361 SNVCEMQWRK ETKNFALLFT APQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle