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Protein Overview: SHC1_RAT

General Information:
Name(s) found: SHC1_RAT [Swiss-Prot]
Description(s) found:
Found 11 descriptions.
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  • SHC-transforming protein 1 OS=Rattus norvegicus GN=Shc1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 469 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    cytosol [UNKNOWN]
    endosome membrane [IDA]
    plasma membrane [UNKNOWN][IMP]
    Biological Process: cell-cell adhesion [UNKNOWN]
    neuron differentiation [IMP]
    neuron projection development [IMP]
    positive regulation of vasoconstriction [IMP]
    Ras protein signal transduction [UNKNOWN]
    response to organic cyclic substance [IEP]
    response to nicotine [IEP]
    response to hydrogen peroxide [IEP]
    aging [IPI]
    response to toxin [IEP]
    positive regulation of smooth muscle cell proliferation [IMP]
    MAPKKK cascade [UNKNOWN]
    activation of MAPK activity [UNKNOWN][IMP]
    heart development [UNKNOWN]
    response to hypoxia [IEP]
    response to insulin stimulus [IEP]
    angiogenesis [UNKNOWN]
    response to glucocorticoid stimulus [IEP]
    organ regeneration [IEP]
    actin cytoskeleton organization [IMP]
    actin cytoskeleton reorganization [UNKNOWN]
    Molecular Function: phosphotyrosine binding [IPI]
    protein binding [UNKNOWN][IEA][IPI]
    phosphoprotein binding [IPI]
    insulin receptor binding [UNKNOWN]
    protein complex binding [IPI]
    insulin-like growth factor receptor binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKLSGGGGR RTRVEGGQLG GEEWTRHGSF VNKPTRGWLH PNDKVMGPGV SYLVRYMGCV  60
   61 EVLQSMRALD FNTRTQVTRE AISLVCEAVP GAKGAMRRRK PCSRPLSSIL GRSNLKFAGM 120
  121 PITLTVSTSS LNLMAADCKQ IIANHHMQSI SFASGGDPDT AEYVAYVAKD PVNQRACHIL 180
  181 ECPEGLAQDV ISTIGQAFEL RFKQYLRNPP KLVTPHDRMA GFDGSAWDEE EEELPDHQYY 240
  241 NDFPGKEPPL GGVVDMRLRE GAARPTLPST QMPSHLGATL PIGQHVTGDH EVRKQMLPPP 300
  301 PCPGRELFDD PSYVNIQNLD KARQAGGGAG PPNPSVNGSA PRDLFDMKPF EDALRVPPAP 360
  361 QSMSMAEQLQ GESWFHGKLS RREAEALLQL NGDFLVREST TTPGQYVLTG LQSGQPKHLL 420
  421 LVDPEGVVRT KDHRFESVSH LISYHMDNHL PIISAGSELC LQQPVDRKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle