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Protein Overview: gi|194422121, gi...

General Information:
Name(s) found: gi|83585644 [NCBI NR]
gi|194439000 [NCBI NR]
gi|194422121 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|83585644|ref|ZP_00924287.1| COG0013: Alanyl-tRNA synthetase [Escherichia coli 101-1] [NCBI NR]
  • gi|194439000|ref|ZP_03071084.1| alanyl-tRNA synthetase [Escherichia coli 101-1] [NCBI NR]
  • gi|194422121|gb|EDX38124.1| alanyl-tRNA synthetase [Escherichia coli 101-1] [NCBI NR]
    • Organism: Escherichia coli 101-1
    Length: 876 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKSTAEIRQ AFLDFFHSKG HQVVASSSLV PHNDPTLLFT NAGMNQFKDV FLGLDKRNYS  60
   61 RATTSQRCVR AGGKHNDLEN VGYTARHHTF FEMLGNFSFG DYFKHDAIQF AWELLTSEKW 120
  121 FALPKERLWV TVYESDDEAY EIWEKEVGIP RERIIRIGDN KGAPYASDNF WQMGDTGPCG 180
  181 PCTEIFYDHG DHIWGGPPGS PEEDGDRYIE IWNIVFMQFN RQADGTMEPL PKPSVDTGMG 240
  241 LERIAAVLQH VNSNYDIDLF RTLIQAVAKV TGATDLSNKS LRVIADHIRS CAFLIADGVM 300
  301 PSNENRGYVL RRIIRRAVRH GNMLGAKETF FYKLVGPLID VMGSAGEDLK RQQAQVEQVL 360
  361 KTEEEQFART LERGLALLDE ELAKLSGDTL DGETAFRLYD TYGFPVDLTA DVCRERNIKV 420
  421 DEAGFEAAME EQRRRAREAS GFGADYNAMI RVDSASEFKG YDHLELNGKV TALFVDGKAV 480
  481 DAINAGQEAV VVLDQTPFYA ESGGQVGDKG ELKGANFSFA VEDTQKYGQA IGHIGKLAAG 540
  541 SLKVGDAVQA DVDEARRARI RLNHSATHLM HAALRQVLGT HVSQKGSLVN DKVLRFDFSH 600
  601 NEAMKPEEIR AVEDLVNTQI RRNLPIETNI MDLEAAKAKG AMALFGEKYD ERVRVLSMGD 660
  661 FSTELCGGTH ASRTGDIGLF RIISESGTAA GVRRIEAVTG EGAIATVHAD SDRLSEVAHL 720
  721 LKGDSNNLAD KVRSVLERTR QLEKELQQLK EQAAAQESAN LSSKAIDVNG VKLLVSELSG 780
  781 VEPKMLRTMV DDLKNQLGST IIVLATVVEG KVSLIAGVSK DVTDRVKAGE LIGMVAQQVG 840
  841 GKGGGRPDMA QAGGTDAAAL PAALASVKGW VSAKLQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..465] PSI-BLAST 1000.0 The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase
    2 View Details [466..781] PSI-BLAST 49.045757 Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)
    3 View Details [782..876] Pfam 21.769551 No description for PF02272.10 was found. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  6.00693881794242 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  2.99105702052936 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.46505535069103 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.29229136935761 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  1.72324031407565 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.47976803533584 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.30216701059664 bayes_pls_golite062009
  • DNA binding
    		•  1.1862497958336 bayes_pls_golite062009
  • binding
    		•  1.11470390774037 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.80781620905336 bayes_pls_golite062009
  • transcription factor activity
    		•  0.566858624145031 bayes_pls_golite062009
  • RNA binding
    		•  0.0221706730298825 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.00572514744734753 bayes_pls_golite062009
    2
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.43002999363006 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.43002999363006 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.41942428925617 bayes_pls_golite062009
  • ligase activity
    		•  6.32830458335651 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  5.71383204545219 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  2.36340232855305 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  1.80163029560755 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  1.77810600842868 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  1.73190731100586 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  1.56431758015114 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.30665379023529 bayes_pls_golite062009
  • binding
    		•  0.904147650999471 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.819460789497064 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.776772138477575 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.619194216414817 bayes_pls_golite062009
  • DNA binding
    		•  0.586146825669637 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.236808757312849 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle