| General Information: |
|
| Name(s) found: |
PI3K2_DICDI
[Swiss-Prot]
|
| Description(s) found:
Found 3 descriptions. SHOW ALL |
|
| Organism: | Dictyostelium discoideum |
| Length: | 1857 amino acids |
Gene Ontology: |
|
| Cellular Component: |
phosphoinositide 3-kinase complex
[IEA]
cell leading edge [TAS] cell cortex [IDA] membrane [TAS] cytosol [TAS] |
| Biological Process: |
[NOT]chemotaxis
[IGI][IMP]
negative chemotaxis [IGI] regulation of cell morphogenesis [IGI] G-protein coupled receptor protein signaling pathway [IMP] regulation of adenylate cyclase activity [IMP] cellular component movement [IGI] phosphoinositide-mediated signaling [ISS] [NOT]actin filament polymerization [IGI] response to cAMP [IGI] chemotaxis to cAMP [IGI] |
| Molecular Function: |
1-phosphatidylinositol-3-kinase activity
[ISS]
|
| Sequence: |
|
| Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51
| | | | | |
1 MKMSEGIISP LSLSSESSEQ QQAAIRKFSN GSNGSGGGGG SNLSVNSSNS GSNNSIRKSS 60
61 TLMYNGPLPS INDGKELLLE NSKPKVVELV NTFNHKPLST IHSVHNEIPP PAIEKEKKEI 120
121 INTISNSGVT KYMTALEILD STINTPLNRS RSGSIGSKPI CNNLTSSSSS SSTTATTPSP 180
181 TTTSNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNTTST TTTTTSILIS 240
241 SSPPPSSSSS SSSNDEQFNN NNNNNNSNSG GSSRMITSKS QIKPLIVTSN TAATTTTTTT 300
301 TNTSAPTTPT NRVQSSLDDL LFNLPTIPSN VPTVNGGPKI SAVPKKVSSS KLLIPPSSNV 360
361 SSSSNITLSL SSSSPSSSSS SSTSTVVPIV QLSSSNSTNS PSTSLPTTPR LSQPTTSYTQ 420
421 LIPSQQQQQP TESNSSSNTN TTTTSSSSSS SSSSLTISSP QPSNNSIRIS AFGRSSTQFT 480
481 ISSNGIPSSP GQVSNKDYNN IGNLSNSSGE RVKNKQYSML NISKKTILDE SDISSSPRSI 540
541 GSPNSIRASI SSQLPPSLSS IGGGGGGGSG PNVVSNKPLV VKKPSTSEHI KKENIWRQTM 600
601 IPLTKEDHIK VVFEGIPGKR VIQKFLIDKT PIEIKSKFFE DLKDGDLLNG LTQLPSLIPE 660
661 HYELKVLSVN STISNETLPL RRQTLMQACN ISRLFPKLHL ILKSESTTIL DGASTTTTTT 720
721 TTTTTTTANQ SSNIITKSNS SLDLTINNSN EIIDVKGHIQ AELEIFELIG TSFTRVLDQG 780
781 QEVVSFRRDF AQFRLSNFTS TRNDLSQMIY VSSEPLPLTI PNKITIMVLL PGDGKIIKRV 840
841 DCCPNSSVGD VKKEIFKKFA MIDRVHTQGK TQDDFVLKVT GFREYILCIH ELGNLTSRQR 900
901 FYPTGSGGDF SLMDYDYIRQ CVGKNQTVEL SLTNNSILSL NQVSEKVSFI DKILETSDFD 960
961 DYDEDLDSIN SNSFDDLKQS IQQQQQQQIQ TVINIKETNK ENKDSNKENK DSSSNNNNNN1020
1021 NNNNNNNNNN NNNNNNNNNN NGNNNGNNSN NNSNSNISRG SIDSEGNGSG SGNGSEQPTL1080
1081 IGVQNFSLPN NSKLPINIVK RLFRVNIAGL RNLNFNNNED ARNKFADGKN NQPNVFVMAE1140
1141 LYYGGELLTN PVFTPIAQLA SYGDGSVEFP NWEKGIAFTI PIRYLPRAAR ASFTVYVTTI1200
1201 SEALESQMDE VVSKSIPIGW SNCLLMNHKG MLRMGPTAFR LWDDGRRANP IGTCVDNQAA1260
1261 KQPIILLVEF ESFIRPIVYV DTALQSMMVN DSSSISSNGV ESPSIVSFSS SAASSSPLPS1320
1321 SPLPSPVGLK KLDLDEARRL KALMDSDPLV QLSAEDKKLV YGYRHIYKSK PKALAKFLLS1380
1381 VNWIDPDQVT DAYRQMNDWA LLKPVQALEI LDAKFADEHV RNFAIKIINS FSDAEFSDFL1440
1441 LQLTQVLKYE PYHNSDLTHI LIQRALSNRS RIGHFFFWFL KSEMHTPEIE ERYGLLLEGY1500
1501 LRSCGTHRQD LIKQNQVLKS LHTVAMAVKQ TNGSSERKKV LMEGLSKIKF PDTFQLPLDP1560
1561 RWEAKGLIID KCRYMDSKKL PLWLVFENVE PHAKPLTVIF KVGDDLRQDI LTLQVLRIMD1620
1621 KFWKNSGMDL RLQPYKCIAT GDGIGMLEVV LNANTIANIN KDAGGTGALL EEKTLVNWLK1680
1681 ECNKTEAEYN KAVETFILSC AGYVVATYVM GIGDRHSDNI MITKLGHLFH IDFGHFLGNY1740
1741 KKKYGFKRER APFIFTPQYM AIVGGKDSEN FKRFVTTCCS AYNILRKNTD LFINLFQLML1800
1801 STGIPELQVA EDIDYLRKAL APGLSDEEAA EEFTKNISVA LNTKTVLLND IFHGWAH |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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| Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
| Confidence of classification: | 0.59 |
Source: Reynolds et al. (2008)