Protein Overview: DPOE1_DICDI

General Information:
Name(s) found:	DPOE1_DICDI [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|74854710\|sp\|Q54RD4.1\|DPOE1_DICDI RecName: Full=DNA polymerase epsilon catalytic subunit A; Short=DNA polymerase II subunit A [NCBI NR] gi\|60467818\|gb\|EAL65833.1\| putative DNA polymerase epsilon subunit A [Dictyostelium discoideum] [NCBI NR] DNA polymerase epsilon catalytic subunit A OS=Dictyostelium discoideum GN=pole PE=3 SV=1 [Swiss-Prot]
Organism:	Dictyostelium discoideum
Length:	2380 amino acids
Gene Ontology:
Cellular Component:	replication fork [ISS] epsilon DNA polymerase complex [ISS]
Biological Process:	lagging strand elongation [ISS] DNA replication [ISS] leading strand elongation [ISS] nucleotide-excision repair [ISS] mismatch repair [ISS]
Molecular Function:	nucleotide binding [ISS] DNA binding [ISS] 3'-5' exonuclease activity [ISS] DNA-directed DNA polymerase activity [IEA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQKWNENKK NKDEKDENDK YVGFKNYEKE GWLLNMQPGS SKDGLDIEKA SLELFFIQDD  60
   61 ATSFRVWIPY NPYFYIYVKE GHQSEVESYL KSTYEKDIAG IDIMDKEDLD LENHLSGLKR 120
  121 KYLKIRFHNV STLLSVRNDL FPIIKRNKQK SNTSEAYEDE SLNKILNSYY NKGNNNNNNH 180
  181 QNYNNNNNQN NNNFNKELNK DDNNNNNSKL NKQATEYILD IREYDVPYYV RAAIDLNIRV 240
  241 GLWYTVIKNG RLTTVNELTT RVDRPDPKVL AYDIETTKLP LKFPDSSIDS IMMISYMLDK 300
  301 QGYLIVNREI VSEDIKDFEY TPKPEYYGPF TVFNEPDEKS VLERFFSEIK REKPHIFVSY 360
  361 NGDMFDWPFV ESRAEYHGLS MFHQIGFRND NGEYRSKINP HMDAFCWVKR DSYLPHGSHG 420
  421 LKAVTREKLR YDPLELDPEL MLKSAQEDPE TLANYSVSDA VATYYLYMNY VHPFIFSLCT 480
  481 IIPMNPDDVL RKGSGTLCEA LLMTQAFKAD VIFPNKHKDD INSMYKGHLL ESETYVGGHV 540
  541 ECLESGVFRS DIPTNFSLDP ASIEKHMGNI DQVLKFALKE GGIPLDTVSN YQEVKEDVLK 600
  601 KFTLLKENPK QQSHPLIYHL DVSAMYPNII LTNKLQPTAV VNDEVCATCV YNKPESQCQR 660
  661 TLDWQWRGDY SPSNQSEYRL ILQQLESEKF GDGDERKSFL SLSEEKRNEL LRKRLKEYSR 720
  721 KVYRKTHQIT QEIRSDTICM RENSFYVDTV RLFRDRRYVF KNHHRDWKIK YDQAMQESGG 780
  781 TNSVAVVAAQ GMVVLYESLQ LAHKCILNSF YGYVMRKGAR WYSMQMAGIV THTGSNIIKE 840
  841 AREVVEQMGR PLEIDTDGIW CILPSHFPEN YTLKSASTGK KVTFSYICEM LNEKVAKSFT 900
  901 NHQYQDYNAE TNTYTIRDEC SILFECDGPY RCMLIPTSKE KDVKLKKRYA VFNREGRICE 960
  961 LKGFEIKRRG ELKLIKLFQS EVFKEFLGGD SLEGCYQSVG AVANRWLDIL DSHAENYEEK1020
 1021 DLIELITESS NMSRKLEEYG TQKSSAISTA KKLAEFLGDD MIKDKGLSCQ YIISNKPAGS1080
 1081 PITERALPVA IFDADFETRC HYLRRWTKSP SGDLDIRELI DWDYYRQRLS GVIQKIITIP1140
 1141 AALQNVTNPV PRVIHPDWIL KEIRRNEDGR QQTSITSFFE KTEDNDQDND NDNDNDNDND1200
 1201 NDNSKPQQTD DIENMFSSRF KDLPAFNPKV TKFKRSKQSS SDVSSLLIKK SKSSIETFTN1260
 1261 EQEKQIMETK TPSIDKDFQG WLSISKKKWK IQRLLKKRRQ RLGGSLFDSD SFRIGSKLTN1320
 1321 RESSSSSFFK SQSDIIKKGY WNIISIEPIY GGEPGIYQMW SLIEDQLIPI KVDIGRVFYL1380
 1381 NSIDTDPYED AQKNTNVIPP RGKQRFNVFS VTMSESQFLE QSKELNTLFT NPMIEGVYET1440
 1441 KVPLDIKAII QCGCVATLSR VSPFFTKIVN SNTRFSLEDI ASKPDKQFHY LAEHNFNQLF1500
 1501 LYHNSRDGKD GYFVLFNMNT QQCSVIFSNP YMAANKIDAR VLNSIKEKLP EITFTMDQKS1560
 1561 SMSLAKKEIG SLIMEYQRKG LPTIILLQVP NAIGILEQIP ILREFPRVPV PYHDNDSMYS1620
 1621 PFNWDVHSLK PLPLRLMDAP KLWVYYANMS RYANIPIGNI PTDNASFMCD ILYARSLVEQ1680
 1681 KHLLWMSDSN FPDLGGSEED DAKFYEELNN VEINNSDCYN QVCFELDIEN LATNTILESI1740
 1741 HLAEIEGILG NELGDESNVA MFDDIKNTSN NSNTKNGANQ NTTNDTTSSF DKLSITNKFR1800
 1801 SAINHQISGC EKEFNILRNL VSKWKLDLVS GSNSKRNEIS SRYSNYLLLH FYRWISSTNS1860
 1861 KLYDPILYRT LHQLMKKVFI QLIFEFKKLG SKIVYANFNK IIICSQKDSI EDARSYCNYI1920
 1921 LAVIKKKELF SWINFKQTNY YHNLLWLNNS NYSGILYFNP LINKNQQQQQ QQQDNADDDD1980
 1981 DDDVSENEEE QQQNKNKKLK KIKNGKIITN WNIAEFLPPQ IQTSFIIIIS DYIYKLHTER2040
 2041 DELNRIQKEQ QQRYLLKQKI STTSSSSNND STAATTTTTK DTINEPTKPD LRKSSTWNEE2100
 2101 EDEDISIPPS SSSSTTTTTS KTKKATSKFD LLIDVNRIFT LLDHFQVNQS SLEFPQLPGG2160
 2161 YLKLNNPPLE FIKFVCHVLS IDKSISSRVS RLRMKLMTSM KVREFSDEAK FKDPCVSFTL2220
 2221 PDVICSSCHS CRDIDLLRNT NTTSISSRLS SQQKSNNNDS DDSDDDNEEN EGDDDNIIRV2280
 2281 PELSCIQCKG HYSKNTIESQ LVEIIQRRSL SYQLQDLRCS KCNDVKSDNL GDICPQCSGQ2340
 2341 WECTQSNNLF SKDLIIFKSI AEYHNFEWLG ETVDSLSKFI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: DPOE1_DICDI

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: