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Protein Overview: DEPD2_MOUSE, PRE...

General Information:
Name(s) found: PREX2_MOUSE [Swiss-Prot]
DEPD2_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|77019277|emb|CAJ33348.1| P-Rex2 protein [Mus musculus] [NCBI NR]
  • gi|123780662|sp|Q3LAC4.1|PREX2_MOUSE RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; Short=PtdIns(3,4,5)-dependent Rac exchanger 2; Short=P-Rex2; AltName: Full=DEP domain-containing protein 2 [NCBI NR]
  • Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein OS=Mus musculus GN=Prex2 PE=2 SV=1 [Swiss-Prot]
  • DEP domain-containing protein 2 - Mus musculus (Mouse) [Swiss-Prot]
  • Tax_Id=10090 P-Rex2 protein [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • DEP domain-containing protein 2 (Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (P-Rex2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • P-Rex2 protein [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Prex2 Isoform 1 of Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Depdc2 Isoform 1 of DEP domain-containing protein 2 [ipi.MOUSE_jw_12may08.contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Depdc2 P-Rex2 protein [zeeyong.fasta]
  • IPI:IPI00890914.1|SWISS-PROT:Q3LAC4-1|TREMBL:Q8BY00|ENSEMBL:ENSMUSP00000027056|REFSEQ:NP_083801 Tax_Id=10090 Gene_Symbol=Prex2 Isoform 1 of Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein [ipi.MOUSE.fasta.20090209]
  • Isoform 1 of Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein OS=Mus musculus GN=Prex2 [011711_HMR.fasta]
    • Organism: Mus musculus
    Length: 1598 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    intracellular [IEA]
    Biological Process: regulation of Rho protein signal transduction [IEA]
    intracellular signaling pathway [IEA]
    G-protein coupled receptor protein signaling pathway [UNKNOWN]
    Molecular Function: protein binding [IEA]
    guanyl-nucleotide exchange factor activity [IEA]
    Rho guanyl-nucleotide exchange factor activity [IEA]
    Rac GTPase activator activity [UNKNOWN]
    Rac guanyl-nucleotide exchange factor activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDESAREVD KQLRLRVCVL SELQKTERDY VGTLEFLVSA FLHRMNQCAA AKVDKNVTEE  60
   61 TVKMLFSNIE EILIVHKEFL KVVEECLYPE PSAQQEVGAC FLHFKDKFRI YDEYCSNHEK 120
  121 AQKLLLELNK IRTIRTFLLN CMLLGGRKNT DVPLEGYLVT PIQRICKYPL LLKELLKRTP 180
  181 RRHSDYTAVM EALQAMKAVC SNINEAKRQM EKLEVLEEWQ AHIEGWEGSN ITDTCTEMLM 240
  241 CGVLMKISSG NIQERVFFLF DNLLVYCKRK HRRLKNSKAS TDGYRYVFRG RINTEVMEVE 300
  301 NVDDGTADFH SSGHIVVNGW KIHNTAKNKW FVCMAKSPEE KHEWFEAILK ERERRKGLKL 360
  361 GMEQDTWVMI SEQGEKLYKM MCKQGNLIKD RKRKLTTFPK CFLGSEFVSW LLEIGEIHRP 420
  421 EEGVHLGQAL LENGIIHHVT DKHQFKPEQM LYRFRYDDGT FYPRSEMQDV ISKGVRLYCR 480
  481 LHSLFTPVVR DKDYHLRTYK SVVMANKLID WLIAQGDCRT REEAMIFAVG LCDNGFMHHV 540
  541 LEKSEFKDEP LLFRFFADEE MEGSNMKHRL MKHDLKVVEN VIAKSLLIKS NEGSYGFGLE 600
  601 DKNKVPIIKL VEKGSNAEMA GMEVGKKIFA INGDLVFLRP FPEVDCFLKS CLNSRKPLRV 660
  661 LVSTKPRETV KIPDSADGLG FQIRGFGPSV VHAVGRGTVA AAAGLHPGQC IIKVNGINVS 720
  721 KETHASVIAH VTACRKYKRP MKQDSIQWVY DSLESAQEDI QKSHSKPPGD GAGDAFECKV 780
  781 EDVIDKFNTM AIIDGKKEHV SLTVDNVHLE YGVVYEYDST AGTKCNVVEK MVEPKGFFSL 840
  841 TAKILEALAK SDEHFVQNCT SLNSLNEVIA TDLQSKFTSM CSERIEHVCH RISSYGRFSR 900
  901 VLKNRAWPTF KQAKPKISPL HSSDFCPTNC HVNVMEVSYP KTSTSLGSAF GVQLDSRKHN 960
  961 SHDKENKSVE PGKLSPMVYI QHTITTMAAP SGLSLGHKDG HGLQYLLKEE DLETQDIYHK1020
 1021 LLGKLQTALK EVEMSVCQID DLLSSITYSP KLERKTTECV TPMDSDNEKG ERNSKRVCFN1080
 1081 VAGDEQEDSG HDTVSNRDSY SDCNSNRNSI ASFTSICSSQ CSSYFHSDEM DSGDELPISV1140
 1141 RISHDKQDKI HTCLEQLFSQ IDSIITLLKG QAVIRPFDQT KYLTPGRGLQ EFQQEMEAKL1200
 1201 SCPRRLRLHL KQDPWNLPSS IQALAQSIRK HAEEVKCRIL LALLEYSDSE TQLRRDMVFC1260
 1261 QSLVATVCAF SEQLMAALNQ MFDNSKENEM ETCEASRRWL DQIANAGVLF HFQSLLSPNL1320
 1321 KDEQAMLEDT LVALFDLEKV SFFFKPSEED PLVANVPLTY QVEGSRQALK VYFYMDSYHF1380
 1381 EQLPQRLKNG GGFKIHPVLF SQALESMEGY CYRDNISVEE FQAQINTASL EKVKQYNQKL1440
 1441 RAFYLDKSNS PPNTTSKAAY IDKLMKPLNA LDELYRLITS FIRSKRIAAC VNTPCSASGV1500
 1501 GLLSVSSELC DRLGACHIIM CSSGVHRCTL SVTLEQTITL ARSHGLPPRY IMQAMDVMRK1560
 1561 QGARVQNTAK NLGVRDRTPQ SAPRLYKLCE PPPPVGEE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle