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Protein Overview: RGA4_SCHPO

General Information:
Name(s) found: RGA4_SCHPO [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Probable Rho-type GTPase-activating protein 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rga4 PE=1 SV=2 [Swiss-Prot]
    • Organism: Schizosaccharomyces pombe 972h-
    Length: 933 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSGTTLHLD RLSLETPSER TCFCIKCWES VPSTSQVWFG GKCWHSDCFK CVNCNKKLDP  60
   61 SSEDFSQDDQ KQIFCKLCVD ICNGCSTPIC EFNAVSNSQA NHPCCSNCRA FINSNAFGKF 120
  121 KGQHYCLPCL RKQDEENQKA VMESASGFIP LRNIAQTAEN TSLTGQNQGF QNPHFIASDS 180
  181 PSSVLSGRMQ NTSSPTNSLR PQLKVQTNGY ETPGDINSAK SYKDIQKDFL LKPKNSFVKT 240
  241 SPSPLANGPS FRSANASPFD SCDSFHSGSS IPIEPVSSRQ SSVVNNNSVQ QPVAYHAFVQ 300
  301 SPTENGTLPQ LPKNESVVNP PPLRRSSTMN YKSVSTTTSP SKYGYVSGRI ALSPIHLRGA 360
  361 LRDVTNKCNL KVPRNRNSLS NLDEYYVNGL ESDETPTKAR FPRYPTVFNK LDDKRLSSEP 420
  421 NGLKKRLTNS SNYEASPRAK SLNLSQVSLH QACEPEYNRS SLVRASDVFT SNVFDATEES 480
  481 ANELAIRISE LQAEVGTLLL EATSLASIIE QQTPVSPEAF KQELVADLNY RLDYLRKSFQ 540
  541 PELSTLLLRR DALSTTVSKL QNAYSTVMEE TAYLNVKNTE LVSLNNQLER ELAYLREQQH 600
  601 KKRTSSSFGI FNNDKKSNRT ISTPSPRESF SRLQMVASSL GFRPKDNKDK ESGGYNKRNS 660
  661 KIDLKKSFSK RFHWKRDSPH MSSTPSISEE HLASEEQEDF VPAVGHCKLC GKYSNELRAH 720
  721 YQDCVSSTID RQYQSKKSES PVWALNPDDF DQNRLTLLRV PTLIVSCINF IESYGMDFEG 780
  781 LYRKSGATSQ MKKIVALLRN EDTVLDPSED ISAVTSVFKQ YLRNLPNPII TYDQYFPFIT 840
  841 AANCASFQDK LDGFIMVIKS LPPAHAEILQ LIIRHLARVA AYSHANRMTS KNLAVVFSPT 900
  901 LIRDPDNSRD VIDMTVKNYS LAFLIDHVHE VFA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] PSI-BLAST 22.69897 Complex of LMO4 LIM domains 1 and 2 with the ldb1 LID domain
    2 View Details [139..330] FFAS03 1.13 No description for 2fj7I was found.
    3 View Details [331..608] FFAS03 1.81 Tropomyosin
    4 View Details [609..933] PSI-BLAST 59.522879 Crystal Structure of the Human Beta2-Chimaerin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.32420977112004 bayes_pls_golite062009
  • protein binding
    		•  1.39455913713025 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.18816040284456 bayes_pls_golite062009
  • DNA binding
    		•  1.00346200943179 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.86280381479968 bayes_pls_golite062009
  • transcription factor activity
    		•  0.441713135779151 bayes_pls_golite062009
  • receptor activity
    		•  0.230063209127305 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • Rho GTPase activator activity
    		•  4.58620967349979 bayes_pls_golite062009
  • Rac GTPase activator activity
    		•  4.48279904625182 bayes_pls_golite062009
  • GTPase regulator activity
    		•  2.70614727793157 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  2.68579854252375 bayes_pls_golite062009
  • binding
    		•  2.15139804299723 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  2.06038764955701 bayes_pls_golite062009
  • enzyme regulator activity
    		•  1.9750017471254 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.95738547986197 bayes_pls_golite062009
  • protein binding
    		•  1.29100556128076 bayes_pls_golite062009
  • myosin heavy chain kinase activity
    		•  1.15190288326422 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  1.09070479183477 bayes_pls_golite062009
  • diacylglycerol binding
    		•  1.04839041514795 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.03886555863373 bayes_pls_golite062009
  • Rho guanyl-nucleotide exchange factor activity
    		•  0.967362611034944 bayes_pls_golite062009
  • Ras guanyl-nucleotide exchange factor activity
    		•  0.958295643211986 bayes_pls_golite062009
  • actin binding
    		•  0.841767135550505 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.717730683557543 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.38794676982412 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.298334474872045 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0455432286632499 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle