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Protein Overview: Myo95E-PI

General Information:
Name(s) found: Myo95E-PI / FBpp0099960 [FlyBase]
Description(s) found:
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  • gi|78706802|ref|NP_001027204.1| myosin 95E, isoform I [Drosophila melanogaster] [NCBI NR]
  • gi|71854580|gb|AAZ52540.1| myosin 95E, isoform I [Drosophila melanogaster] [NCBI NR]
  • The gene Myosin 95E is referred to in FlyBase by the symbol Dmel\Myo95E (CG5501, FBgn0039157). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19980549..19987217. It has the cytological map location 95E6. It is reported to have molecular function</span>: ATPase activity, coupled. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • type=protein; loc=3R:complement(19981738..19981861,19981967..19982094,19982156..19982308,19982369..19982504,19982566..19982897,19983113..19983809,19983869..19984116,19984214..19984536,19984598..19984745,19984811..19984905,19984964..19985048,19985198..1998 [fly-100309-contam.fasta]
  • CG5501-PI, isoform I [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Myosin 95E CG5501-PI, isoform I [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(19981738..19981861,19981967..19982094,19982156..19982308,19982369..19982504,19982566..19982897,19983113..19983809,19983869..19984116,19984214..19984536,19984598..19984745,19984811..19984905,19984964..19985048,19985198..19985261,19985370..19985371); ID=FBpp0099960; name=Myo95E-PI; parent=FBgn0039157,FBtr0100520; dbxref=FlyBase_Annotation_IDs:CG5501-PI,FlyBase:FBpp0099960,GB_protein:AAZ52540.1,REFSEQ:NP_001027204,GB_protein:AAZ52540; MD5=cbb0ec2e6fd629c2aa585626d16bdc3f; length=844; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(19981738..19981861,19981967..19982094,19982156..19982308,19982369..19982504,19982566..19982897,19983113..19983809,19983869..19984116,19984214..19984536,19984598..19984745,19984811..19984905,19984964..19985048,19985198..19985261,19985370..19985371); ID=FBpp0099960; name=Myo95E-PI; parent=FBgn0039157,FBtr0100520; dbxref=FlyBase_Annotation_IDs:CG5501-PI,FlyBase:FBpp0099960,GB_protein:AAZ52540.1,REFSEQ:NP_001027204,GB_protein:AAZ52540; MD5=cbb0ec2e6fd629c2aa585626d16bdc3f; length=844; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Myosin 95E, isoform I OS=Drosophila melanogaster GN=Myo95E PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 844 amino acids

    Gene Ontology:
    Cellular Component: myosin complex [IEA][NAS]
    Biological Process: NONE FOUND
    Molecular Function: ATP binding [IEA]
    ATPase activity, coupled [NAS]
    motor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESYLISKLI LREIQWECTL PITRITDPII GERNFHIFYQ LLLGADLQLL KSLKLYRNVE  60
   61 KYELLRNTTA MEEDRMNFHY TKRSLDVLGL SCEESNSIFR VIAVVLKLGN FIFVPITNID 120
  121 GTEGCQVSNV YEVQETAQLL NMEAQILINC LTRANSTNSA QEDVGCEMDA RQAATNRNTL 180
  181 CRTLYSRLFT WLVNKINESL KSTQREKNLA LLDFYGFEAL DHNSFEQFAI NYSAEKIHQN 240
  241 FVFHVLRSEQ ELYIREGLEW SRIDYFDNES ICELIDKPSY GILSLINEPH LNSNDALLLR 300
  301 VQQCCAGHPN FMTTGSNSMC FQIRHYASVV NYSIHRFLEK NSDMLPKYIS AAFYQSKLSL 360
  361 VQSLFPEGNP RRQVTKKPST LSSNIRTQLQ TLLAIVKHRR SHYVFCIKPN EGKQPHQFDM 420
  421 ALVQHQVRYM SLMPLVHLCR TGHCYHLLHV KFFHRYKLLN SLTWPHFHGG SQVEGIALII 480
  481 RNLPLPSAEF TIGTKNVFVR SPRTVYELEQ FRRLRISELA VLIQTMFRMY HARKRFQRMR 540
  541 HSQMIISSAW RTWRAREEYR SLKYKRQVRW AIDIIGRYYR QWKIRQFLLT IPLRLPPNTL 600
  601 SPLSTEWPVA PAFLADASRH LRSIYHRWKC YIYRNSFDQT ARNRMREKVT ASIIFKDRKA 660
  661 SYGRSVGHPF VGDYVRLRHN QQWKKICAET NDQYVVFADI INKIARSSGK FVPILLVLST 720
  721 SSLLLLDQRT LQIKYRVPAS EIYRMSLSPY LDDIAVFHVK ASEFGRKKGD FVFQTGHVIE 780
  781 IVTKMFLVIQ NATGKPPEIH ISTEFEANFG QQTVIFSFKY GGMSDLAQGP PKVTRKANRM 840
  841 EIIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..536] PSI-BLAST 137.0 Myosin S1, motor domain
    2 View Details [537..596] deduced N/A No confident structure predictions are available.
    3 View Details [597..844] PSI-BLAST 4.522879 Tropomyosin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.77927104644254 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  1.24902799058407 bayes_pls_golite062009
  • motor activity
    		•  1.24134836429447 bayes_pls_golite062009
  • actin binding
    		•  0.787185996273667 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.579837407295159 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.498311726132348 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.398651949563863 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.329606804913681 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.310343974731494 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.308125979591209 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle