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Protein Overview: D2R-PE

General Information:
Name(s) found: D2R-PE / FBpp0099566 [FlyBase]
Description(s) found:
Found 10 descriptions.
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  • The gene Dopamine 2-like receptor is referred to in FlyBase by the symbol Dmel\D2R (CG33517, FBgn0053517). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:19898715..19922226. It has the cytological map location 19A4. There is experimental evidence that it has the molecular function</span>: dopamine receptor activity, coupled via Gi/Go; dopamine receptor activity. There is experimental evidence that it is involved in the biological process</span>: dopamine receptor signaling pathway. 4 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 572 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGGFGDAEL LQRTATVARE TLGNRTAPST TSYDGGGSGD VGVAGGLAGT AGGGVGGAGG  60
   61 SGGSTFMLLL ENFNDYFPNY NGSTVSGTST IAPGVAITGS RGSGLLLEQN LTGLYLDGYR 120
  121 LNCTNETLNL TDSCGELRVV DHNYWALILI LFPILTLFGN ILVILSVCRE RSLQTVTNYF 180
  181 IVSLAIADLL VAVVVMPFAV YFLVNGAWAL PDVVCDFYIA MDVICSTSSI FNLVAISIDR 240
  241 YIAVTQPIKY AKHKNSRRVC LTILLVWAIS AAIGSPIVLG LNNTPNREPD VCAFYNADFI 300
  301 LYSSLSSFYI PCIIMVFLYW NIFKALRSRA RKQRAARKPH LSELTGGSVI ENIAQTRRLA 360
  361 ETALDSSRHA SRILPDEAAT NTASGSNEEE DENAISPDID DCHVIVNDKS TEFMLATVVE 420
  421 ETGNVAMKPL SFVRYGVQEA MTLARNDSTL STTSKTSSRK DKKNSQASRF TIYKVHKASK 480
  481 KKREKSSAKK ERKATKTLAI VLGVFLFCWL PFFSCNIMDA MCAKFKKDCR PGLTAYMMTT 540
  541 WLGYINSFVN PVIYTIFNPE FRKAFKKIMH MG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..117] deduced N/A No confident structure predictions are available.
    2 View Details [118..413] PSI-BLAST 35.522879 Rhodopsin
    3 View Details [414..572] FFAS03 5.66 Rhodopsin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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