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View Structure Prediction Details

Protein: D2R-PE
Organism: Drosophila melanogaster
Length: 572 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for D2R-PE.

Description E-value Query
Range
Subject
Range
D2R-PD - The gene Dopamine 2-like receptor is referred to in FlyBase by the symbol Dmel\D2R (CG33517, FBgn005...
320.0 [0..67] [572..1]

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Predicted Domain #1
Region A:
Residues: [1-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGGFGDAEL LQRTATVARE TLGNRTAPST TSYDGGGSGD VGVAGGLAGT AGGGVGGAGG  60
   61 SGGSTFMLLL ENFNDYFPNY NGSTVSGTST IAPGVAITGS RGSGLLLEQN LTGLYLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [118-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYRLNCTNET LNLTDSCGEL RVVDHNYWAL ILILFPILTL FGNILVILSV CRERSLQTVT  60
   61 NYFIVSLAIA DLLVAVVVMP FAVYFLVNGA WALPDVVCDF YIAMDVICST SSIFNLVAIS 120
  121 IDRYIAVTQP IKYAKHKNSR RVCLTILLVW AISAAIGSPI VLGLNNTPNR EPDVCAFYNA 180
  181 DFILYSSLSS FYIPCIIMVF LYWNIFKALR SRARKQRAAR KPHLSELTGG SVIENIAQTR 240
  241 RLAETALDSS RHASRILPDE AATNTASGSN EEEDENAISP DIDDCHVIVN DKSTEF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [414-572]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLATVVEETG NVAMKPLSFV RYGVQEAMTL ARNDSTLSTT SKTSSRKDKK NSQASRFTIY  60
   61 KVHKASKKKR EKSSAKKERK ATKTLAIVLG VFLFCWLPFF SCNIMDAMCA KFKKDCRPGL 120
  121 TAYMMTTWLG YINSFVNPVI YTIFNPEFRK AFKKIMHMG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.66
Match: 1f88A
Description: Rhodopsin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle