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Protein Overview: FBpp0307778

General Information:
Name(s) found: FBpp0307778 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • type=protein; loc=3R:join(743596..743853,748314..748546,748669..748890,748956..749199,749254..749414,749476..749550,751268..751374,751616..751731,751798..752053,766397..767662,768024..768510,770697..770775); ID=FBpp0307778; name=Cdep-PE; parent=FBgn0265082,FBtr0336809; dbxref=FlyBase:FBpp0307778,FlyBase_Annotation_IDs:CG44193-PE,REFSEQ:NP_001036676,GB_protein:ABI31137; MD5=84f3cb5c8eb92f3efcd17dae9b91d1c4; length=1167; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1167 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEA]
    cytoplasm [IEA]
    extrinsic to membrane [IEA]
    Biological Process: regulation of Rho protein signal transduction [IEA]
    Molecular Function: actin binding [ISS]
    Rho guanyl-nucleotide exchange factor activity [ISS]
    cytoskeletal protein binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLADMGTAS RSAGGEGGRH YDLATGGAGS GGHPVGGGLP GGRMTHSLST PSGVDGTPST  60
   61 PRHRGGKKLT VRIQMLDDSI TMFQVQAKAL GRVLFEQVCR QLNLLEADYF GLEYQEVSTH 120
  121 TKYWLDLEKP MNRQVGLSLI DPVLRFCIKF YTPDPAQLEE EYTRYLFCLQ IKRDLATGSL 180
  181 QCNDNTAALM ASYIVQASCG DFVPEDYPDH TYLSSYRFVP NQDATMQRKI MENHKKHVGQ 240
  241 SPAEADLNLL ETARRCELYG MKMHPAKDVE GVPLNLAVAH MGITVFQNIT RINTFSWAKI 300
  301 RKISFKRKRF LVKLHPEGYG YYKDTVEFFF EGRNECKNFW KKCVENHGFF RCTAVQNTPR 360
  361 RKTRVLSRGS SFRYSGKTQK QIIEFVRENY VKRQNFQRSQ SFRQGPLNAS SRSQSHTYVN 420
  421 SSISANPLLP IDTAAWDYRN QCSDSMTPSL TKKAADTLDR RRDNPIGHMR SQVTAAQVEI 480
  481 YQTKNYAADS PTSQEEAECS AAGAERQHHS AVAMDKLNSN RSLSPQGPQS WTSPSHSSHH 540
  541 QQRGPDPARV HPGDHNTDGY YGINGNMSLD RRGEITTPPT RYDLTLGSDK SSSLSRSEAG 600
  601 TYDVIQAEIQ HAKRQELATG VATASHQNGN GNGNGHTLST QHDIEAEVKK RKWPTEPSYF 660
  661 LAKELLMTER TYKKDLDVLN TTFRQVLSLG DVEQLQPLFE LLDSLAQHHN LFLRDIEHRM 720
  721 VQWEGRGGHE AHRIGDVMMK HMAALPIYDE YVQTHLDILH CMNDMYEGDE RFRQVYKEFE 780
  781 QQKVCYLPIG ELLLKPLNRL LHYQLILERL CDYYGEEHID YADAMAVHHL LVRSTKGIRS 840
  841 QLPDSANFVE LCELQRDINF EQLVQPHRRL IRQGCLLKHS KRGLQQRMFF LFSDLLLYGS 900
  901 KSPLDQSFRI LGHVPVRSLL TENAEHNTFS IFGGQCAITV SAGTTAEKTL WLAELSKAAA 960
  961 DIKNRPPNMQ LQLTTLKNCS SSEEGLDLFG LSNGNNSSLN SSVNGGGPLT TQQQKLQLQQ1020
 1021 QQQNRTQPSR SNTALHVCWH RGATVGLGDH LIAAEHQLSG YLLRKFKNSS GWQKLWVVFT1080
 1081 SFCLYFYKSY QDEFALASLP LLGYTVGPPG HQDAVQKEFV FKLSFKNHVY FFRAESAHTY1140
 1141 NRWLEVLRST TQTQDFKNVH SHAVLGN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..351] PSI-BLAST 77.522879 Erythroid membrane protein 4.1R
    2 View Details [352..541] deduced N/A No confident structure predictions are available.
    3 View Details [542..1036] PSI-BLAST 48.221849 No description for 2pz1A was found.
    4 View Details [1037..1167] PSI-BLAST 15.0 No description for 2yryA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.0685299680095634 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle