Protein Overview: PIAS2_MOUSE

General Information:
Name(s) found:	PIAS2_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|56404605\|sp\|Q8C5D8.2\|PIAS2_MOUSE RecName: Full=E3 SUMO-protein ligase PIAS2; AltName: Full=Protein inhibitor of activated STAT2; AltName: Full=Protein inhibitor of activated STAT x; AltName: Full=Msx-interacting zinc finger protein; AltName: Full=DAB2- [NCBI NR] E3 SUMO-protein ligase PIAS2 OS=Mus musculus GN=Pias2 PE=1 SV=2 [Swiss-Prot] Splice Isoform 1 of Protein inhibitor of activated STAT2 [ipi.MOUSE.v3.06.fasta] Tax_Id=10090 Splice Isoform 1 of Protein inhibitor of activated STAT2 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] E3 SUMO-protein ligase PIAS2 (Protein inhibitor of activated STAT2) (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Pias2 Isoform 1 of E3 SUMO-protein ligase PIAS2 [mouse-ipi-250309-contam.fasta] protein inhibitor of activated STAT 2 isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_09-14-2009_con_reversed.fasta] Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) [nr-271106-contam.fasta] E3 SUMO-protein ligase PIAS2 isoform 1 [Mus musculus] [NCBI-RefSeq_mouse_na_05-17-2010_reversed.fasta] IPI:IPI00453655.2\|SWISS-PROT:Q8C5D8-1\|TREMBL:Q3V3U5\|ENSEMBL:ENSMUSP00000110425\|REFSEQ:NP_032628 Tax_Id=10090 Gene_Symbol=Pias2 Isoform 1 of E3 SUMO-protein ligase PIAS2 [ipi.MOUSE.fasta.20090209] Isoform 1 of E3 SUMO-protein ligase PIAS2 OS=Mus musculus GN=Pias2 [011711_HMR.fasta] sp\|Q8C5D8\|PIAS2_MOUSE E3 SUMO-protein ligase PIAS2 OS=Mus musculus GN=Pias2 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
Organism:	Mus musculus
Length:	621 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] nuclear body [IDA]
Biological Process:	transcription [IEA] transcription, DNA-dependent [IDA] protein sumoylation [IDA] positive regulation of transcription [UNKNOWN] androgen receptor signaling pathway [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [IDA] regulation of transcription [UNKNOWN] regulation of androgen receptor signaling pathway [UNKNOWN] regulation of osteoblast differentiation [IMP] positive regulation of dendrite morphogenesis [UNKNOWN]
Molecular Function:	nucleic acid binding [IEA] DNA binding [IDA] zinc ion binding [IEA] protein binding [IPI] androgen receptor binding [UNKNOWN] RNA polymerase II transcription factor activity [IDA] metal ion binding [IEA] estrogen receptor binding [UNKNOWN] transcription activator activity [IDA] glucocorticoid receptor binding [UNKNOWN] SUMO ligase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADFEELRNM VSSFRVSELQ VLLGFAGRNK SGRKHDLLMR ALHLLKSGCS PAVQIKIREL  60
   61 YRRRYPRTLE GLCDLSTIKS SVFSLDGSSS PVEPDLPVAG IHSLPSTSIT PHSPSSPVGS 120
  121 VLLQDTKPTF EMQQPSPPIP PVHPDVQLKN LPFYDVLDVL IKPTSLVQSS IQRFQEKFFI 180
  181 FALTPQQVRE ICISRDFLPG GRRDYTVQVQ LRLCLAETSC PQEDNYPNSL CIKVNGKLFP 240
  241 LPGYAPPPKN GIEQKRPGRP LNITSLVRLS SAVPNQISIS WASEIGKNYS MSVYLVRQLT 300
  301 SAMLLQRLKM KGIRNPDHSR ALIKEKLTAD PDSEIATTSL RVSLMCPLGK MRLTIPCRAV 360
  361 TCTHLQCFDA ALYLQMNEKK PTWICPVCDK KAAYESLILD GLFMEILNDC SDVDEIKFQE 420
  421 DGSWCPMRPK KEAMKVTSQP CTKVESSSVF SKPCSVTVAS DASKKKIDVI DLTIESSSDE 480
  481 EEDPPAKRKC IFMSETQSSP TKGVLMYQPS SVRVPSVTSV DPAAIPPSLT DYSVPFHHTP 540
  541 VSSMSSDLPG LDFLSLIPVD PQYCPPMFLD SLTSPLTASS TSVTTTSPHE SSTHVSSSSS 600
  601 RSETGVITSS GRNIPDIISL D

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PIAS2_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: