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Protein Overview: exo-3

General Information:
Name(s) found: exo-3 / CE38407 [WormBase]
Description(s) found:
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  • WBGene00001372 locus:exo-3 status:Confirmed UniProt:Q564V5 protein_id:CAI79211.1 [WormBase]
  • gi|71989539|ref|NP_001021585.1| EXOnuclease family member (exo-3) [Caenorhabditis elegans] [NCBI NR]
  • gi|62553978|emb|CAI79211.1| C. elegans protein R09B3.1b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • CE38407 WBGene00001372 locus:exo-3 status:Confirmed TR:Q564V5 protein_id:CAI79211.1 [wormpep150.fasta]
  • 38407 WBGene00001372 locus:exo-3 status:Confirmed TR:Q564V5 protein_id:CAI79211.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE38407 WBGene00001372 locus:exo-3 status:Confirmed UniProt:Q564V5_CAEEL protein_id:CAI79211.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE38407 WBGene00001372 locus:exo-3 status:Confirmed UniProt:Q564V5_CAEEL protein_id:CAI79211.1| [wormORF-contam.fasta]
  • EXOnuclease family member (exo-3) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein R09B3.1b [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE38407 WBGene00001372 locus:exo-3 status:Confirmed UniProt:Q564V5 protein_id:CAI79211.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • Isoform of G5EBR7, DNA-(apurinic or apyrimidinic site) lyase OS=Caenorhabditis elegans GN=exo-3 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 186 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEALink to PubMed article]
    Biological Process: embryonic development [IMPLink to PubMed article]
    DNA repair [IEALink to PubMed article][IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    endonuclease activity [IEALink to PubMed article]
    nuclease activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRKAEEAP APKLASIFTK KVKPAEEDNN QKSWKFVCWN VAGLRACVKK SDFKEVLAEE  60
   61 PDLVFLGETK CKEWPPEMEE TFKNYTKTLV VSTEKNGGYA GVGLLSKCAP MKVHKGIGDP 120
  121 EFDTAGRLII AEFSKFYFIG AYVPNSGAKL VNLEKRGRWE KLLTEKMKEM DEKKPVIYGE 180
  181 SRIKSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..186] PSI-BLAST 47.69897 THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.23505510330573 bayes_pls_golite062009
  • hydrolase activity
    		•  0.79070010643157 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.71596812518333 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle