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View Structure Prediction Details

Protein: exo-3
Organism: Caenorhabditis elegans
Length: 186 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for exo-3.

Description E-value Query
Range
Subject
Range
gi|109082628, gi... - gi|109082640|ref|XP_001090240.1| PREDICTED: APEX nuclease isoform 8 [Macaca mulatta], gi|109082638|r...
gi|90078218 - gi|90078218|dbj|BAE88789.1| unnamed protein product [Macaca fascicularis]
192.0 [0..2] [186..28]

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Predicted Domain #1
Region A:
Residues: [1-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRKAEEAP APKLASIFTK KVKPAEEDNN QKSWKFVCWN VAGLRACVKK SDFKEVLAEE  60
   61 PDLVFLGETK CKEWPPEMEE TFKNYTKTLV VSTEKNGGYA GVGLLSKCAP MKVHKGIGDP 120
  121 EFDTAGRLII AEFSKFYFIG AYVPNSGAKL VNLEKRGRWE KLLTEKMKEM DEKKPVIYGE 180
  181 SRIKSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.69897
Match: 1bixA
Description: THE CRYSTAL STRUCTURE OF THE HUMAN DNA REPAIR ENDONUCLEASE HAP1 SUGGESTS THE RECOGNITION OF EXTRA-HELICAL DEOXYRIBOSE AT DNA ABASIC SITES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.23505510330573 bayes_pls_golite062009
hydrolase activity 0.79070010643157 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.71596812518333 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle