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Protein Overview: unc-42

General Information:
Name(s) found: unc-42 / CE39164 [WormBase]
Description(s) found:
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  • WBGene00006778 locus:unc-42 status:Partially_confirmed UniProt:G5EBS8 protein_id:CAA94780.3 [WormBase]
  • gi|86564116|ref|NP_505519.3| UNCoordinated family member (unc-42) [Caenorhabditis elegans] [NCBI NR]
  • gi|77799282|emb|CAA94830.3| C. elegans protein F58E6.10, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|77799281|emb|CAA94780.3| C. elegans protein F58E6.10, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • CE39164 WBGene00006778 locus:unc-42 Homeobox domain status:Partially_confirmed TR:Q20455 protein_id:CAA94780.2 [wormpep150.fasta]
  • 39164 WBGene00006778 locus:unc-42 Homeobox domain status:Partially_confirmed TR:Q20455 protein_id:CAA94780.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE39164 WBGene00006778 locus:unc-42 Homeobox domain status:Partially_confirmed UniProt:Q20455_CAEEL protein_id:CAA94830.3 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE39164 WBGene00006778 locus:unc-42 Homeobox domain status:Partially_confirmed UniProt:Q20455_CAEEL protein_id:CAA94830.3| [wormORF-contam.fasta]
  • CE39164 WBGene00006778 locus:unc-42 Homeobox domain status:Partially_confirmed TR:Q20455 protein_id:CAA94780.3 [wormpep160-contam.fasta]
  • Hypothetical protein F58E6.10 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • UNCoordinated family member (unc-42) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE39164 WBGene00006778 locus:unc-42 Homeobox domain status:Partially_confirmed UniProt:Q20455 protein_id:CAA94830.3 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE39164 WBGene00006778 locus:unc-42 Homeobox domain status:Partially_confirmed UniProt:G5EBS8 protein_id:CAA94780.3 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE39164 WBGene00006778 locus:unc-42 status:Partially_confirmed UniProt:G5EBS8 protein_id:CAA94780.3 [wormpep246-ecoli-contam.fasta]
  • Isoform of L8E946, Uncharacterized protein OS=Caenorhabditis elegans GN=unc-42 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 264 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    neuron fate specification [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDNLLNGAN GASTVSQFQE KVKDLGVSLH DFTAYYPSSL DTVSASLRPI SDPSSDGAFK  60
   61 KIKTEGLGGS VFGSSIAGVT NTPARRRHRT TFTQEQLQEL DAAFQKSHYP DIYVREELAR 120
  121 ITKLNEARIQ VWFQNRRAKH RKHEKQLNKA INPPHSFLSN PANTLMRQGM YPAALNRDGF 180
  181 WYQSYQRPMP YPTASPSYSN SFTNPIANFG HSITSFQADD EFYQKSLALR MTTTPSAATA 240
  241 ATSLANINYQ QTQPSEASTN PPSI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..149] PSI-BLAST 23.39794 Paired protein
    2 View Details [150..264] MSA 7.994997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.57523737355937 bayes_pls_golite062009
  • DNA binding
    		•  3.00143272905695 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.89825020286436 bayes_pls_golite062009
  • transcription factor activity
    		•  2.53664874743748 bayes_pls_golite062009
  • binding
    		•  1.68817361068715 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.56629498736977 bayes_pls_golite062009
  • transcription activator activity
    		•  1.26247803652791 bayes_pls_golite062009
  • protein binding
    		•  1.16239587634422 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.14821760889085 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.20862059645422 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle