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Protein Overview: nas-37

General Information:
Name(s) found: nas-37 / CE38034 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00003553 locus:nas-37 Zinc metalloproteinase nas-37 status:Confirmed UniProt:Q93243 protein_id:CAI58633.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 685 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    extracellular region [IDALink to PubMed article]
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed article]
    molting cycle, protein-based cuticle [IMPLink to PubMed articleLink to PubMed article]
    collagen and cuticulin-based cuticle development [IMPLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    ecdysis, collagen and cuticulin-based cuticle [IMPLink to PubMed article]
    proteolysis [IEALink to PubMed article]
    Molecular Function: meprin A activity [IEALink to PubMed article]
    zinc ion binding [ISSLink to PubMed article]
    protein binding [ISSLink to PubMed article]
    astacin activity [IDALink to PubMed article][IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSQACLKVC LALIGLVSIV STAYIANDVV SDYAEVKELL AAFYRKHAKK YGHDYDPAAI  60
   61 QAIAENMDKS VKNDKTEATV NRKLWNEVFE NDIILTLPQA ESLLSESNSP RSRRQAHPDP 120
  121 RNFWPNLTIS YEFYGGEETW RQLIRSAIRH VEQNVCFKFK ENGGDRDGLR YYRGNGCWSN 180
  181 VGRVGGRQLV SIGYGCDSLG IVSHETLHAL GLWHEQSRDD RDNFISIVAD KITRGTEGNF 240
  241 AKRTAANSDN LGQPYDLGSV MHYGAKSFAY DWSSDTIKTR DWRYQNTIGQ RDGLSFKDAK 300
  301 MINTRYCSNV CQRSLPCLNE GYTDPNNCGR CRCPSGYGGT YCETVEYTSC GGSLTASSSY 360
  361 KKIESGIVQP DANCVWRIRN PGGNVEVMFD QVNFQCADPC QSYVEVKYLS QKTSTGARLC 420
  421 CSLPSVIRSE GDDVIIILRG TPNTAVGWRG FTLKYRAIGG TPITPATVRP TYATTTRPYW 480
  481 TRTTRPTPTT TVAPDTASWS AWGEWSACSQ PCGGCGTKTR VRACYGGNQV CPGSNLDRES 540
  541 CNAHACAKPK KGMICNGRLL LPCDLLAKLN FGSNNYLNPK LKQSGFARSS TLPLPRISQR 600
  601 KPVFVNELEV HPPTERFLSS STRRVKRQTA NRFCEKRFIY QCPTALLTIQ MEYKPDTQGT 660
  661 NDAYFQQYPE CCSGYTPRRG VCYKN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] deduced N/A No confident structure predictions are available.
    2 View Details [75..196] PSI-BLAST 46.154902 STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
    3 View Details [197..319] PSI-BLAST 4.0 No description for 2eroA was found.
    4 View Details [320..685] PSI-BLAST 13.39794 Solution structure of dimeric form of properdin by X-ray solution scattering and analytical ultracentrifugation


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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