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Protein Overview: dgk-1

General Information:
Name(s) found: dgk-1 / CE38268 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00000958 locus:dgk-1 status:Partially_confirmed UniProt:Q58AU6 protein_id:CCD63966.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 794 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: response to food [IMPLink to PubMed article]
    synaptic transmission, cholinergic [IMPLink to PubMed article]
    negative regulation of locomotion [IMPLink to PubMed article]
    regulation of oviposition [IMPLink to PubMed article]
    regulation of locomotion [IMPLink to PubMed article]
    signal transduction [IEALink to PubMed article]
    dopamine receptor signaling pathway [IMPLink to PubMed article]
    activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IEALink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]
    diacylglycerol kinase activity [IDALink to PubMed article][IEALink to PubMed article]
    Rho GTPase binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAEGHNVDA NLVDMRPNHG HYFVKKTFGK PAYCHHCCDK IWGMLTTGYS CEMCNFVCHE  60
   61 KCLRTVVSYC SSVALQLIKN PVAHTWSAPC LIKRKYCCVC RKRTDDALSV ECEVCEYYVH 120
  121 VDCSDLAVSD CKEAATYVAN MESANTVQYH HMREGNLPKE SKCIVCRKTC FSTECLAGMR 180
  181 CEWCGQTAHA VCYRQMDKEC DFGVLRKIML PPMCLTIPRT ELPMEQLLNI SSHDQPQSLS 240
  241 SPSKIQADDV STSGEDVKER EDFEIIRVFD GNNSYRSQDS LRRYHVVRFY VQEKEDPHDH 300
  301 AVFVGNLPVS LAQRQYERIL LKLLGAKEKP FTAIGPIYFE YGSLIITFNT PKAATAAVQK 360
  361 LQSAIYEEKK LIVLCLPNVQ PQMIPKDVEP LLVLVNVKSG GCQGTELIQS FRKLLNPFQV 420
  421 FDVLNGGPLV GLYVFRNIPK YKILACGGDG TIGWVLQCLD IAKQDAACFS PPCGIVPLGT 480
  481 GNDLARVLRW GGGYTGEENP MDILKDVIEA DTVKLDRWAV VFHEEERNQP TSSGNQTEMN 540
  541 EQTMNNPEDQ TSMIIMNNYF GIGIDADVCL KFHNKRDANP EKFQSRLFNK TQYAKIGLQK 600
  601 MFFERTCKDL WKRIELEVDG RIIELPNIEG IVVLNLLSWG SGANPWGTSK EEGNFSKPTH 660
  661 YDGLLEVVGI SDVSRLGLIQ SKLAAGIRIA QGGSIRITTH EEWPVQVDGE PHIQPPGTIT 720
  721 ILKSALKAQM LKKAKKSRRG GATNATSLTH PHPETSESMS GPLGVPSTLG DPNHGKTTPD 780
  781 NTAADSDEEG DAFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] FFAS03 2.69 No description for 2db6A was found.
    2 View Details [113..278] PSI-BLAST 38.39794 No description for 2i13A was found.
    3 View Details [279..400] PSI-BLAST 11.221849 Transcription factor IIIA, TFIIIA
    4 View Details [401..794] PSI-BLAST 21.39794 No description for 2jgrA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.59793470114903 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.617293965719078 bayes_pls_golite062009
  • catalytic activity
    		•  0.616333600617445 bayes_pls_golite062009
  • DNA binding
    		•  0.424758271537657 bayes_pls_golite062009
  • protein binding
    		•  0.347976394954253 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.283680459495274 bayes_pls_golite062009
    4
    Term Confidence Notes
  • kinase activity
    		•  1.93010589087203 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.6993468998669 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.62136531467279 bayes_pls_golite062009
  • transferase activity
    		•  1.1287574677626 bayes_pls_golite062009
  • catalytic activity
    		•  0.704900964793432 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle