Protein Overview: dpyd-1

General Information:
Name(s) found:	dpyd-1 / CE38489 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00016103 locus:dpyd-1 Dihydropyrimidine dehydrogenase [NADP(+)] status:Partially_confirmed UniProt:Q18164 protein_id:CCD65682.1 [WormBase] gi\|97536128\|sp\|Q18164.2\|DPYD_CAEEL RecName: Full=Dihydropyrimidine dehydrogenase [NADP+]; Short=DHPDHase; Short=DPD; AltName: Full=Dihydrouracil dehydrogenase; AltName: Full=Dihydrothymine dehydrogenase [NCBI NR] gi\|71984108\|ref\|NP_508927.2\| DihydroPYrimidine Dehydrogenase family member (dpyd-1) [Caenorhabditis elegans] [NCBI NR] gi\|62630064\|gb\|AAK39195.2\| Hypothetical protein C25F6.3 [Caenorhabditis elegans] [NCBI NR] Dihydropyrimidine dehydrogenase [NADP(+)] OS=Caenorhabditis elegans GN=dpyd-1 PE=3 SV=2 [Swiss-Prot] CE38489 WBGene00016103 status:Partially_confirmed SW:Q18164 protein_id:AAK39195.2 [wormpep150.fasta] [wormpep130-phg-ecoli-orf-rand.fasta] 38489 WBGene00016103 status:Partially_confirmed SW:Q18164 protein_id:AAK39195.2 [wormpep150-phg-orf-ecoli-rand.fasta] CE38489 WBGene00016103 locus:dpyd-1 status:Partially_confirmed UniProt:Q18164 protein_id:AAK39195.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE38489 WBGene00016103 locus:dpyd-1 status:Partially_confirmed UniProt:Q18164 protein_id:AAK39195.2\| [wormORF-contam.fasta] Hypothetical protein C25F6.3 [Caenorhabditis elegans] [nr-271106-contam.fasta] Probable dihydropyrimidine dehydrogenase [NADP+] (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase) [nr-271106-contam.fasta] C25F6.3 [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE38489 WBGene00016103 locus:dpyd-1 status:Partially_confirmed UniProt:Q18164 protein_id:CCD65682.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE38489 WBGene00016103 locus:dpyd-1 status:Partially_confirmed UniProt:Q18164 protein_id:CCD65682.1 Dihydropyrimidine dehydrogenase [NADP(+)] [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1059 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] membrane [IEA]
Biological Process:	electron transport [IEA] 'de novo' pyrimidine base biosynthetic process [IEA] glutamate biosynthetic process [IEA] removal of superoxide radicals [IEA] UMP biosynthetic process [IEA]
Molecular Function:	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor [IEA] oxidoreductase activity [IEA] FAD binding [IEA] oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [IEA] electron carrier activity [IEA] thioredoxin-disulfide reductase activity [IEA] dihydroorotate dehydrogenase activity [IEA] 4 iron, 4 sulfur cluster binding [IEA] iron-sulfur cluster binding [IEA] dihydroorotate oxidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPKPNTTSP TNNLPLLSKD SPDIESLLIL NPKVQDKANA VPSAVTKKNK HNWKRNEEKG  60
   61 CGSTCGESKL KNDFRDIKHT TLSERGALKE AMRCLKCADA PCQKSCPTQL DVKSFITSIS 120
  121 NKNYYGAARQ ILSDNPLGLT CGMICPTSDL CVGSCNLQAS EEGAINIGGL QQYACDVFKQ 180
  181 MNVRQIVSKE VRENRNASHK EQVALIGCGP ASISCASFLA RLGYTDITIY EKRAYIGGLS 240
  241 SAEIPQFRLP YDVVDFEIQL ARDIGVQIET NRPLGKDGLT LAKLKEQGAA AVFIGIGNPE 300
  301 PKIDPLFEGL TIENGFYTSK NYLPAVAAAS KPGMCGCKRT PLPTMRGRVV VLGAGDTAMD 360
  361 CATSALRCGA SRVTIAFRKG FTGIRAVPEE MEAAKEEKCE FLPFSAPRKI NVKDGRIVSI 420
  421 EFNKTEQDDN GKWYEDEEQI VILKCDYVIS AFGSTLKEDA VLSALQPCQL NKWGGIEVDS 480
  481 TTQQTSEKWV FAGGDVAGVA ETTVESVNDG KIAAWNMHRY IQSLHGNQVS ETPELPQFFT 540
  541 PIDEVDISVD MCGVKFENPF GLASAPPTTS GPMCRRAFEQ GWGFILTKTY GLDKDLVTNV 600
  601 SPRIVRGSTS GPLYGPNQGS FMNIELISEK SCEYWLQCIR ELKRDHPTKI VIASIMCVYN 660
  661 KADWIELATK SEEAGADILE LNLSCPHGMG EKGMGLACGQ SPEIVKEICR WVRACVKIPF 720
  721 FPKMTPNITD VREIARAARD GGASGVTATN TVSSLMHMKA DGNAWPAIGS TKRTTYGGMS 780
  781 GSAIRPIAMK AVSSIANELD GFPIMATGGI ESAETGLGFL MAGASVLQVC SAVQNQDFTV 840
  841 VDDYCTGLKA LLYLSGAESL KNWDGQSPPI EKHQKGKPIL LQGQKKMPFF GKYRDEREKL 900
  901 EAIKLSESNL LDTENYHFAS RPDTQVSRVP TVEDVIGKAL PRIGPYVTLD NQEQKVAIID 960
  961 DDMCINCGKC YMTCNDSGYQ AITFDPVTHQ PHVTEDDCTG CTLCYSVCPI PECIEMVPRT1020
 1021 GPWKAPKRGV KPSVEPGTPK VVKVDQRGRV ILDTTGGMQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: dpyd-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: