Protein Overview: SIR2D_DICDI

General Information:
Name(s) found:	SIR2D_DICDI [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|60464347\|gb\|EAL62496.1\| NAD(+)-dependent deacetylase, silent information regulator protein (Sir2) family protein [Dictyostelium discoideum] [NCBI NR] NAD-dependent deacetylase sir2D OS=Dictyostelium discoideum GN=sir2D PE=2 SV=1 [Swiss-Prot] \|Protein\| gene: DDB0219946 on chromosome: 5 position 3346251 to 3348043 [dicty_predictions_protein.fasta]
Organism:	Dictyostelium discoideum
Length:	542 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC] chromatin silencing complex [ISS]
Biological Process:	regulation of transcription, DNA-dependent [ISS] protein amino acid deacetylation [ISS] chromatin silencing [ISS]
Molecular Function:	DNA binding [ISS] zinc ion binding [ISS] NAD or NADH binding [ISS] NAD-dependent histone deacetylase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKRSLENNE LNEIQNNQNK NNNNKINKEI PSDNTPLKKL KSINSLEQLQ EVDEDEDLDV  60
   61 EIDTKLINKL DKKGRKYEFV GEGYSDEEQI SDDYEDDESS EYEYGYENED ELLDDEDHLD 120
  121 NINEIKKIQK KLVNTETSTS ITNTSSTTTT STSTTTTTTT KTQINETILL DILNNNKDEV 180
  181 DDEIQRIGNN VGNSKEEEGE EEEENIELVA RSFIYKHIQE KKSLGIDPIE FTKDIGFKLE 240
  241 LEKDDDAWEI ITAFLTRKKV AVNLFLNYLK YNTLARPYRK KIATLDLSTF EKVCQLFESS 300
  301 KNIVIITGAG VSVSCGIPDF RSKGGVYETI EKKYNLPRPE SLFDIHYLRA NPLPFFEFAK 360
  361 EIFPGNHKPS PTHSFIKLLD EKGKLLRNYT QNIDTLEHVA GIDREKLVNC HGSFSTATCI 420
  421 TCKLTVDGTT IRDTIMKMEI PLCQQCNDGQ SFMKPDIVFF GENLPDRFDQ CVLKDVKDID 480
  481 LLIVMGSSLQ VQPVSLLPDI VDKQIPQILI NRELVAQPHE FDYVYLGDCD QFVQDLLNKV 540
  541 KW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: SIR2D_DICDI

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: