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Protein Overview: POLR3K

General Information:
Name(s) found: POLR3K [HGNC (HUGO)]
Description(s) found:
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  • gi|66350794|emb|CAI95605.1| polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa [Homo sapiens] [NCBI NR]
  • gi|14336676|gb|AAK61210.1|AE006462_2 RNA polymerase III subunit CII [Homo sapiens] [NCBI NR]
  • gi|116242768|sp|Q9Y2Y1.2|RPC10_HUMAN RecName: Full=DNA-directed RNA polymerase III subunit RPC10; Short=RNA polymerase III subunit C10; AltName: Full=DNA-directed RNA polymerase III subunit K; AltName: Full=RNA polymerase III subunit C11; Short=RPC11; Sho [NCBI NR]
  • polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa [HGNC (HUGO)]
  • polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa [HGNC (HUGO)]
  • DNA-directed RNA polymerases III 12.5 kDa polypeptide (EC 2.7.7.6) (RNA polymerase III subunit K) (RNA polymerase III C11 subunit) (HsC11p) (hRPC11) - Homo sapiens (Human) [Swiss-Prot]
  • DNA-directed RNA polymerase III subunit RPC10 OS=Homo sapiens GN=POLR3K PE=1 SV=2 [Swiss-Prot]
  • RNA polymerase III subunit CII [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III subunit C11) (RPC11) (HsC11p) (hRPC11) (DNA-directed RNA polymerases III 12.5 kDa polypeptide) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 DNA-directed RNA polymerases III 12.5 kDa polypeptide [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=POLR3K DNA-directed RNA polymerase III subunit RPC10 [human-ipi-250309-contam.fasta]
  • DNA-directed RNA polymerases III 12.5 kDa polypeptide (RNA polymerase III subunit K) (RNA polymerase III C11 subunit) (HsC11p) (hRPC11) [nr-271106-contam.fasta]
  • IPI:IPI00008461.2|SWISS-PROT:Q9Y2Y1|ENSEMBL:ENSP00000293860|REFSEQ:NP_057394|H-INV:HIT000064892|VEGA:OTTHUMP00000067145;OTTHUMP00000081389 Tax_Id=9606 Gene_Symbol=POLR3K DNA-directed RNA polymerase III subunit RPC10 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=POLR3K DNA-directed RNA polymerase III subunit RPC10 ENSG00000161980 IPI00008461 IPI00745532 [drosphohumanreversed.fasta]
  • Q9Y2Y1;Q1W6H4;Q96S35; RecName: Full=DNA-directed RNA polymerase III subunit RPC10; AltName: Full=DNA-directed RNA polymerase III subunit K; AltName: Full=RNA polymerase III subunit C11; AltName: Full=RNA polymerase III 12.5 kDa subunit; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • DNA-directed RNA polymerase III subunit RPC10 OS=Homo sapiens GN=POLR3K [011711_HMR.fasta]
  • GeneSymbol=POLR3K Synonyms=C11|C11-RNP3|RPC10|RPC11|RPC12.5|hRPC11 DNA-directed RNA polymerase III subunit RPC10 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00008461.2|SWISS-PROT:Q9Y2Y1|ENSEMBL:ENSP00000293860|REFSEQ:NP_057394|H-INV:HIT000064892|VEGA:OTTHUMP00000067145 Tax_Id=9606 Gene_Symbol=POLR3K DNA-directed RNA polymerase III subunit RPC10 [ipi.HUMAN.20110912.fasta]
  • DNA-directed RNA polymerase III subunit RPC10 GN=POLR3K [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 108 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLFCPGCGN GLIVEEGQRC HRFSCNTCPY VHNITRKVTN RKYPKLKEVD DVLGGAAAWE  60
   61 NVDSTAESCP KCEHPRAYFM QLQTRSADEP MTTFYKCCNA QCGHRWRD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] PSI-BLAST 20.0 RBP9 subunit of RNA polymerase II

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA-directed RNA polymerase activity
    		•  8.87472871386782 bayes_pls_golite062009
  • RNA polymerase activity
    		•  8.87472871386782 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  6.30881681756207 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  5.23548851881217 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.66342402708121 bayes_pls_golite062009
  • transferase activity
    		•  3.6513313586587 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.36253105801209 bayes_pls_golite062009
  • binding
    		•  2.58311326284197 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  2.03339710864117 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.8086747972572 bayes_pls_golite062009
  • DNA binding
    		•  1.76634962183736 bayes_pls_golite062009
  • DNA primase activity
    		•  1.01743034310838 bayes_pls_golite062009
  • protein binding
    		•  0.764662055834369 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.672750759084994 bayes_pls_golite062009
  • catalytic activity
    		•  0.434839928397784 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle