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Protein Overview: gi|22136684, gi|...

General Information:
Name(s) found: gi|30686280 [NCBI NR]
gi|22136684 [NCBI NR]
gi|20268737 [NCBI NR]
Description(s) found:
Found 11 descriptions.
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  • gi|30686280|ref|NP_850240.1| AICARFT/IMPCHase bienzyme family protein [Arabidopsis thaliana] [NCBI NR]
  • gi|22136684|gb|AAM91661.1| putative phosphoribosylaminoimidazolecarboxamide formyltransferase [Arabidopsis thaliana] [NCBI NR]
  • gi|20268737|gb|AAM14072.1| putative phosphoribosylaminoimidazolecarboxamide formyltransferase [Arabidopsis thaliana] [NCBI NR]
    • Organism: Arabidopsis thaliana
    Length: 596 amino acids

    Gene Ontology:
    Cellular Component: chloroplast stroma [IDA]
    chloroplast [IDA]
    stromule [IDA]
    Biological Process: response to cold [IEP]
    purine nucleotide biosynthetic process [ISS]
    Molecular Function: catalytic activity [IEA]
    IMP cyclohydrolase activity [IEA][ISS]
    phosphoribosylaminoimidazolecarboxamide formyltransferase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSSAATATS VSARSGDILC GLFRKKSVAP FRFTQPVYRT SLCPSFVAVR AMAESQTAQR  60
   61 NQPQSSGSSG EKQALISLSD KRDLASLGNG LQELGYTIVS TGGTASTLEN AGVSVTKVEK 120
  121 LTHFPEMLDG RVKTLHPNIH GGILARRDVE HHMEALNEHG IGTFDVVVVN LYPFYEKVTA 180
  181 PGGISFEDGI ENIDIGGPAM IRAAAKNHKD VLIVVDSGDY QAVLEYLKGG QSDQQFRRKL 240
  241 AWKAFQHVAA YDSAVSEWLW KQTEGKEKFP PSFTVPLVLK SSLRYGENPH QKAAFYVDKS 300
  301 LAEVNAGGIA TAIQHHGKEM SYNNYLDADA AWNCVSEFEN PTCVVVKHTN PCGVASRDDI 360
  361 LEAYRLAVKA DPVSAFGGIV AFNVEVDEVL AREIREFRSP TDGETRMFYE IVVAPKYTAK 420
  421 GLEVLKGKSK TLRILEAKKN DQGKLSLRQV GGGWLAQDSD DLTPEDISFN SVSDKTPTES 480
  481 ELADAKFAWL CVKHVKSNAI VIAKNNCMLG MGSGQPNRVE SLRIAFKKAG EEAKGAALAS 540
  541 DAFFPFAWKD AVEEACQMGI GVIAEPGGSI RDQDAIDCCK KYGVSLLFTN VRHFRH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..69] PSI-BLAST 45.045757 Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
    2 View Details [70..596] PSI-BLAST 159.0 Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • IMP cyclohydrolase activity
    		•  2.44338227123463 bayes_pls_golite062009
  • phosphoribosylaminoimidazolecarboxamide formyltransferase activity
    		•  2.17104645465987 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  1.79965948308471 bayes_pls_golite062009
  • catalytic activity
    		•  1.70756445127105 bayes_pls_golite062009
  • hydroxymethyl-, formyl- and related transferase activity
    		•  1.51378035087272 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  1.19388272840449 bayes_pls_golite062009
  • deaminase activity
    		•  1.16510523659661 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.03324558866637 bayes_pls_golite062009
  • cytidine deaminase activity
    		•  0.870445440530128 bayes_pls_golite062009
  • binding
    		•  0.46651845554048 bayes_pls_golite062009
  • hydrolase activity
    		•  0.339145951258927 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle