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Protein Overview: ATX1_ARATH

General Information:
Name(s) found: ATX1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|95147534|sp|Q9C5X4.2|ATX1_ARATH RecName: Full=Histone-lysine N-methyltransferase ATX1; AltName: Full=Trithorax-homolog protein 1; Short=TRX-homolog protein 1; AltName: Full=Protein SET DOMAIN GROUP 27 [NCBI NR]
  • gi|30685011|ref|NP_850170.1| ATX1 (ARABIDOPSIS HOMOLOGUE OF TRITHORAX); histone-lysine N-methyltransferase/ phosphatidylinositol-5-phosphate binding [Arabidopsis thaliana] [NCBI NR]
  • Histone-lysine N-methyltransferase ATX1 OS=Arabidopsis thaliana GN=ATX1 PE=1 SV=2 [Swiss-Prot]
  • trithorax 1 (ATX-1) (TRX1) [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Trithorax 1 (ATX-1) (TRX1) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATX1 | ATX1 (ARABIDOPSIS HOMOLOGUE OF TRITHORAX); histone-lysine N-methyltransferase/ phosphatidylinositol-5-phosphate binding | chr2:13462525-13469258 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • Histone-lysine N-methyltransferase, H3 lysine-4 specific ATX1 (H3-K4-HMTase) (Trithorax-homolog protein 1) (TRX-homolog protein 1) (Protein SET DOMAIN GROUP 27) [nr-271106-contam.fasta]
  • DNA binding / nucleic acid binding / protein binding / zinc ion binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATX1, SDG27 | homologue of trithorax | chr2:13455448-13462181 REVERSE LENGTH=1062 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 1062 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    plasma membrane [IDA]
    Biological Process: regulation of flower development [IGI][IMP]
    specification of floral organ identity [IMP]
    histone H3-K4 methylation [IDA]
    Molecular Function: histone-lysine N-methyltransferase activity [IDA]
    phosphatidylinositol-5-phosphate binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MACFSNETQI EIDVHDLVEA PIRYDSIESI YSIPSSALCC VNAVGSHSLM SKKVKAQKLP  60
   61 MIEQFEIEGS GVSASDDCCR SDDYKLRIQR PEIVRVYYRR RKRPLRECLL DQAVAVKTES 120
  121 VELDEIDCFE EKKRRKIGNC ELVKSGMESI GLRRCKENNA FSGNKQNGSS RRKGSSSKNQ 180
  181 DKATLASRSA KKWVRLSYDG VDPTSFIGLQ CKVFWPLDAL WYEGSIVGYS AERKRYTVKY 240
  241 RDGCDEDIVF DREMIKFLVS REEMELLHLK FCTSNVTVDG RDYDEMVVLA ATLDECQDFE 300
  301 PGDIVWAKLA GHAMWPAVIV DESIIGERKG LNNKVSGGGS LLVQFFGTHD FARIKVKQAI 360
  361 SFIKGLLSPS HLKCKQPRFE EGMQEAKMYL KAHRLPERMS QLQKGADSVD SDMANSTEEG 420
  421 NSGGDLLNDG EVWLRPTEHV DFRHIIGDLL IINLGKVVTD SQFFKDENHI WPEGYTAMRK 480
  481 FTSLTDHSAS ALYKMEVLRD AETKTHPLFI VTADSGEQFK GPTPSACWNK IYNRIKKVQN 540
  541 SDSPNILGEE LNGSGTDMFG LSNPEVIKLV QDLSKSRPSS HVSMCKNSLG RHQNQPTGYR 600
  601 PVRVDWKDLD KCNVCHMDEE YENNLFLQCD KCRMMVHAKC YGELEPCDGA LWLCNLCRPG 660
  661 APDMPPRCCL CPVVGGAMKP TTDGRWAHLA CAIWIPETCL SDVKKMEPID GVNKVSKDRW 720
  721 KLMCTICGVS YGACIQCSNN SCRVAYHPLC ARAAGLCVEL ENDMSVEGEE ADQCIRMLSF 780
  781 CKRHRQTSTA CLGSEDRIKS ATHKTSEYLP PPNPSGCART EPYNCFGRRG RKEPEALAAA 840
  841 SSKRLFVENQ PYVIGGYSRL EFSTYKSIHG SKVSQMNTPS NILSMAEKYR YMRETYRKRL 900
  901 AFGKSGIHGF GIFAKLPHRA GDMMIEYTGE LVRPSIADKR EQLIYNSMVG AGTYMFRIDD 960
  961 ERVIDATRTG SIAHLINHSC VPNCYSRVIT VNGDEHIIIF AKRHIPKWEE LTYDYRFFSI1020
 1021 GERLSCSCGF PGCRGVVNDT EAEEQHAKIC VPRCDLIDWT AE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] deduced N/A No confident structure predictions are available.
    2 View Details [242..375] PSI-BLAST 8.69897 DNA methyltransferase DNMT3B
    3 View Details [376..813] PSI-BLAST 4.30103 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
    4 View Details [814..1062] PSI-BLAST 18.30103 No description for 2r3aA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle