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Protein Overview: gi|78100079, gi|...

General Information:
Name(s) found: gi|83754234 [NCBI NR]
gi|78100079 [NCBI NR]
gi|71042216 [NCBI NR]
gi|42543316 [NCBI NR]
gi|42543315 [NCBI NR]
gi|22219370 [NCBI NR]
gi|22219369 [NCBI NR]
gi|22219366 [NCBI NR]
gi|22219365 [NCBI NR]
gi|22219364 [NCBI NR]
gi|22219363 [NCBI NR]
gi|22219362 [NCBI NR]
Description(s) found:
Found 26 descriptions.
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  • gi|83754234|pdb|2B5I|A Chain A, Cytokine Receptor Complex [NCBI NR]
  • gi|78100079|gb|ABB20900.1| interleukin 2 [Homo sapiens] [NCBI NR]
  • gi|71042216|pdb|1Z92|A Chain A, Structure Of Interleukin-2 With Its Alpha Receptor [NCBI NR]
  • gi|42543316|pdb|1PW6|B Chain B, Low Micromolar Small Molecule Inhibitor Of Il-2 [NCBI NR]
  • gi|42543315|pdb|1PW6|A Chain A, Low Micromolar Small Molecule Inhibitor Of Il-2 [NCBI NR]
  • gi|22219370|pdb|1M4C|B Chain B, Crystal Structure Of Human Interleukin-2 [NCBI NR]
  • gi|22219369|pdb|1M4C|A Chain A, Crystal Structure Of Human Interleukin-2 [NCBI NR]
  • gi|22219366|pdb|1M49|B Chain B, Crystal Structure Of Human Interleukin-2 Complexed With Sp- 1985 [NCBI NR]
  • gi|22219365|pdb|1M49|A Chain A, Crystal Structure Of Human Interleukin-2 Complexed With Sp- 1985 [NCBI NR]
  • gi|22219364|pdb|1M48|B Chain B, Crystal Structure Of Human Il-2 Complexed With (R)-N-[2-[1- (Aminoiminomethyl)-3-Piperidinyl]-1-Oxoethyl]-4- (Phenylethynyl)-L-Phenylalanine Methyl Ester [NCBI NR]
  • gi|22219363|pdb|1M48|A Chain A, Crystal Structure Of Human Il-2 Complexed With (R)-N-[2-[1- (Aminoiminomethyl)-3-Piperidinyl]-1-Oxoethyl]-4- (Phenylethynyl)-L-Phenylalanine Methyl Ester [NCBI NR]
  • gi|22219362|pdb|1M47|A Chain A, Crystal Structure Of Human Interleukin-2 [NCBI NR]
    • Organism: Homo sapiens
    Length: 133 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE  60
   61 EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR 120
  121 WITFCQSIIS TLT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|13786858 gi|150261449 gi|219109210, gi... gi|78100079, gi|...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] PSI-BLAST 50.154902 Interleukin-2 (IL-2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytokine receptor binding
    		•  6.47223189691244 bayes_pls_golite062009
  • receptor binding
    		•  5.3304255990112 bayes_pls_golite062009
  • cytokine activity
    		•  5.1883241815362 bayes_pls_golite062009
  • growth factor activity
    		•  4.92105782010612 bayes_pls_golite062009
  • interleukin-10 receptor binding
    		•  3.75864942466928 bayes_pls_golite062009
  • protein binding
    		•  3.26483713001551 bayes_pls_golite062009
  • growth hormone activity
    		•  2.71439518801599 bayes_pls_golite062009
  • hormone activity
    		•  2.52921243340076 bayes_pls_golite062009
  • binding
    		•  2.48265117231403 bayes_pls_golite062009
  • prolactin receptor binding
    		•  2.45721634350294 bayes_pls_golite062009
  • interleukin-6 receptor binding
    		•  2.37535614986843 bayes_pls_golite062009
  • interleukin-12 binding
    		•  2.17594406686308 bayes_pls_golite062009
  • interleukin-27 binding
    		•  1.83998174953013 bayes_pls_golite062009
  • ciliary neurotrophic factor receptor binding
    		•  1.79326213321183 bayes_pls_golite062009
  • interleukin-2 receptor binding
    		•  1.24568403220915 bayes_pls_golite062009
  • interleukin-12 beta subunit binding
    		•  1.10825259714222 bayes_pls_golite062009
  • erythropoietin receptor binding
    		•  0.77580300541347 bayes_pls_golite062009
  • interleukin-4 receptor binding
    		•  0.390049814001731 bayes_pls_golite062009
  • interleukin-3 receptor binding
    		•  0.264629367313661 bayes_pls_golite062009
  • catalytic activity
    		•  0.246169290135575 bayes_pls_golite062009
  • interleukin-12 receptor binding
    		•  0.218984052557791 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.010318258615897 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle