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Protein Overview: ser-1

General Information:
Name(s) found: ser-1 / CE38526 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00004776 locus:ser-1 status:Confirmed UniProt:G5ECV2 protein_id:CCD63420.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 635 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: G-protein coupled receptor protein signaling pathway [IEALink to PubMed article]
    serotonin receptor signaling pathway [IDALink to PubMed article]
    calcium-mediated signaling [IDALink to PubMed article]
    Molecular Function: serotonin binding [IDALink to PubMed article]
    amine binding [IDALink to PubMed article]
    serotonin receptor activity [IDALink to PubMed article]
    rhodopsin-like receptor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIYHFNGVA LFLLPVLCLI GLIGNFLVCV AIATDRRLHN VTNYFLFSLA LADLLVCCIV  60
   61 MPLSIVVEVR HGVWTWSVSM CLLYVYSDVF LCSASIVHMS VISLDRYLGI SQPLRTRNRS 120
  121 KTLIFIKIAI VWVVTLLVSC PIAVLAMHDT ANILRNNQCM IFSRYYIIYG STMTFLIPLC 180
  181 IMGVTYAKTT QLLNKQASIL SQKAGDKFNG NGLRRTMPHR KLGYARTYSA TVNGTIANGK 240
  241 AIGAHGRTMS SISNIANGET ADRLGTSRPS INTNGHKQLQ KASTINKWKS RTSNLVTNFA 300
  301 NKVGRRSSLQ TATQDLANEH KATRVLAVVF ACFFICWTPF FFINFLIGFG GENVQIPDWV 360
  361 ASIFLWLGYV SSTINPIIYT VFNKRFRQAF VRILRCQCFH PLRDSHQMYS RNFTTTIVPD 420
  421 TYTCSRSNQE RTTSVITRDE TRSARSSERP EPSRARSEIS EEPVARTNGK LTSEKKKISL 480
  481 PSFPRVSSSR DSRATTEAST TDEETKPLIP KSTVPATVIN IPEQLINPIK KSLTTIINMP 540
  541 LLDETIPEKA QVHHKSQTLL TSSTLNFATF STCPQQPTRS YSCVDCKKAE KMLSSDVSDM 600
  601 MTTSTASTAS TVNGAPRKHL TLFNHFDSAI KETFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..303] PSI-BLAST 44.30103 Rhodopsin
    2 View Details [304..438] FFAS03 3.74 Rhodopsin
    3 View Details [439..635] MSA 6.053996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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