Protein Overview: itr-1

General Information:
Name(s) found:	itr-1 / CE37906 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00002173 locus:itr-1 Inositol 1,4,5-trisphosphate receptor itr-1 status:Confirmed UniProt:Q9Y0A1 protein_id:CCD63764.1 [WormBase] gi\|71987644\|ref\|NP_001023171.1\| Inositol Triphosphate Receptor family member (itr-1) [Caenorhabditis elegans] [NCBI NR] gi\|56797838\|gb\|AAW30669.1\| Inositol triphosphate receptor protein 1, isoform d [Caenorhabditis elegans] [NCBI NR] gi\|5262809\|emb\|CAB45862.1\| inositol 1,4,5-trisphosphate receptor [Caenorhabditis elegans] [NCBI NR] ref\|NP_501251.2\| inositol 1 4 5-Triphosphate Receptor, DEfecation Cycle abnormal DEC-4, Let-23 Fertility Effector/regulator LFE-1 (324.6 kD) (itr-1) [Caenorhabditis elegans] [NCBI NR] CE37906 WBGene00002173 locus:itr-1 status:Confirmed TR:Q9U3B3 protein_id:AAW30669.1 [wormpep150.fasta] inositol 1 4 5-Triphosphate Receptor, DEfecation Cycle abnormal DEC-4, Let-23 Fertility Effector/regulator LFE-1 (324.6 kD) (itr-1) [Caenorhabditis elegans]gi\|5262809\|emb\|CAB45862.1\| inositol 1,4,5-trisphosphate receptor [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] 37906 WBGene00002173 locus:itr-1 status:Confirmed TR:Q9U3B3 protein_id:AAW30669.1 [wormpep150-phg-orf-ecoli-rand.fasta] CE37906 WBGene00002173 locus:itr-1 status:Confirmed UniProt:Q9U3B3_CAEEL protein_id:AAW30669.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE37906 WBGene00002173 locus:itr-1 status:Confirmed UniProt:Q9U3B3_CAEEL protein_id:AAW30669.1\| [wormORF-contam.fasta] Inositol triphosphate receptor protein 1, isoform d [Caenorhabditis elegans] [nr-271106-contam.fasta] Inositol Triphosphate Receptor family member (itr-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] inositol 1,4,5-trisphosphate receptor [Caenorhabditis elegans] [nr-271106-contam.fasta] CE37906 WBGene00002173 locus:itr-1 status:Confirmed UniProt:Q9U3B3 protein_id:AAW30669.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE37906 WBGene00002173 locus:itr-1 status:Confirmed UniProt:Q9U3B3 protein_id:CCD63764.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE37906 WBGene00002173 locus:itr-1 status:Confirmed UniProt:Q9Y0A1 protein_id:CCD63764.1 Inositol 1,4,5-trisphosphate receptor itr-1 [wormpep246-ecoli-contam.fasta] Isoform of Q9Y0A1, Isoform d of Inositol 1,4,5-trisphosphate receptor itr-1 OS=Caenorhabditis elegans GN=itr-1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	2836 amino acids
Gene Ontology:
Cellular Component:	membrane [IDA][IEA] endoplasmic reticulum [TAS] proteinaceous extracellular matrix [IEA]
Biological Process:	regulation of pharyngeal pumping [IGI][IMP] ion transport [IEA] muscle contraction [IMP] calcium ion transport [IEA] cell adhesion [IEA] blood coagulation [IEA] defecation [IMP] reproduction [IMP ] rhythmic behavior [IMP] elevation of cytosolic calcium ion concentration [IDA]
Molecular Function:	inositol-1,4,5-trisphosphate receptor activity [ISS] ion channel activity [IEA] calcium channel activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKSSMALPS RKLTIANSID HGNNGNLHIG DIISLYTESS SNQEQRGFLS TLGLVDDRCI  60
   61 VELKDGRPES PPKKFRDCLF KVCPVNRYAA QKHLWTEQKR FQTGDSMFDD DLMNKLKVAA 120
  121 DKEREENESE FQKTLGNVIQ YGSMVQLLHV KSNKYITVQK NSPAKRERNA MKVYLDRAGN 180
  181 EGSWFIIEPA YKHYAIGDNV SAGNKISLIP NSVSTTQAGH VKSQLHLSSF NLLDHQSAAE 240
  241 VNCLNEPTEW QVFMFLLFDE NQQNSVKSGD VVRLFHADQQ TFLTLDTIPK QNPPTDVVFL 300
  301 RMTNRPSAAD ATSSRALWEV QVVQTNAYRG GTAKWNKAYR FKHLATDMYL SAEPSQVQVK 360
  361 PAMNGRRASL IYSKTNNPMA MYSDGPNGVT NESTDTTQQN IPSVWVLGPT KSEFPEEDAN 420
  421 LLFQLDPSTF MKSNKEVPRR SYVRLLHQSS DKWVHATNAT EKQNLHYSSK NEKGWVKVIC 480
  481 EKNRVDKETF ALLPVNPDEV RDLDFANDAC KALRNFIKLI KIGQVISKES INSTTQLLID 540
  541 CILFVTNSSD HLADPLKISD FSPSRDRQKL LREQEVLNQV FLLLKAPFLP RQGTTELGPL 600
  601 LSSPSELSDS RNEIFKTMFQ LCYCLLKYSQ VSYRKNQEFL AEKFGEIQEQ IGFDLMAEDT 660
  661 MTAVLHNNPK LLEKYVKTPH VERFVELVRN NRQGKFLDYL ADLCVCRGEA NKKIQELICT 720
  721 SVLSSKHRDI FMDTKIIDGE IEVGWAPNFR KLVDIAEGAK SNSDDAEHLD YYRHQLDLLS 780
  781 QMCQEQQYLA IDPPPERRLM NISQQLPAEL VLQCMSDNRL PYDLRGSFTR LMLHLHVVRG 840
  841 SPMSAIRHAR LWWSIPENVN VSTYESVSVE AYSDGSRMRI GEGIAHKVLA TVETYLMGLR 900
  901 NQSMEERQSV NSSKLTYEIV NLAKALAQFN FYSFNDLLQL TQNLLAIINE GPATEQVPSH 960
  961 RAMVNAIRNM SKSMMRGGNK ENSKDLAKTP SVTAEEAGRT KEGRALNVKT KLIVAEILQF1020
 1021 VMDVRRDYRI TMALSWFKNV FPCDEDGSLM HSASINERMA SELYDAIYRS SGHELHLDGR1080
 1081 DGQLLLAILL QMTMSDYPPL TSIALKVFFR HFTQYQELLE DLKQVQLLVS NNDVENYRQI1140
 1141 DRDLFILKNL TEKSELWVHG DRHHSIDTKE VDEKERTTEH DLLDHDLKSP RAFDSGDSME1200
 1201 ALMAVLNEHY PSIRNECLQL LNRLLIKDDR NDAAVALQEL SDKAPLIAYP LIRQMLVRLT1260
 1261 GMCYRKGDPK PDTMNQQLLK NMRVYEVVLE FISVPHDKKH DHDMMKLITL SHEFLRSFCK1320
 1321 TNKENQSRLY KFISYEKDAK EGMLRVETIE EVGTLVAIFR NNRELASNVP EELIAHIVGL1380
 1381 IEHNSRNPIF LELLQALVCV YDKEIESGQE KVANEICAAS DEVRQLYVDN ASFEELEAMM1440
 1441 KDEKESKGRS SDSRRKLKYH IELVRLLAMC TRGKNGNTEL KCASQIPMDH IVRVVTAKQC1500
 1501 LVEVKTVYLQ LLLHCYIDTD AEMKDAYKTE YVDHILNNLL EDIRSLRVEK LTGAETATLE1560
 1561 HYICHTVTEV LIKFFEAPYS ALQQAKVDVH HHKKTFSEVL LELTYLEKGK LRGSKSSRNW1620
 1621 YRVAECIKRL TKWAEEHNIT LPATLAGPQM SGQTSVRQKW QQAASSAKWI GIGKRLNRQN1680
 1681 TLNPGHRLYG TSNSMTEHTS ANVVTCYHMM IGEFKFYLHP LHAAEGSVLV EVLHTPELLF1740
 1741 PEGSALRDQC ARGGVVAKLI QHCKTLMQNK QDNLCARVLQ TLCKMCDCTK QQLTHQGQQL1800
 1801 RQLLLQRYFG HHNNHHPPLD RQQSKIGEVI EAVKEKKEET WSQERDLYAI QCKLNDAGAS1860
 1861 DLVTDIIIME PSREIFLKAI HLARALLHEG NDKVQHSFYM RMKQKDIHEP FFKAILTRIQ1920
 1921 TAQNRLKSDM MSCSDSKPKV SLSATVSRRS STVLTPLIDA GDTGFNGALF EVPQQVRHPS1980
 1981 ISEMSQLSND LTHSIPDLAP YQDEEKSTDA LPPEVALVEP ILRVLQLLCE NHNSLLQNFL2040
 2041 RKQSDRTNHN LVSETLSFLD TVCGSTKGSL GVFGEIGEHN FSLITQTLAT LTEFCQGPCH2100
 2101 ENQNTMAMQE NGLNIIISLV LNEIKPLADD HMELALEIKS QASKLLLAIM ESRHDGENAN2160
 2161 RVLRNMANMS GGPKQLVHAI KQAYEMTNSN HHMLKSISRD LFRQAEDDLK KKSGPQITVN2220
 2221 TVTLPEINVD ASGIVSIHTE KNISSSLDDK FNDDDIPSVD PREVGHNIYI LAHQLAIHDG2280
 2281 ELEIWLDGSD EKKDDLTREA LNYYKERTAQ IEIVRRDRTL ERVVFPINDI CSYLTKDTKD2340
 2341 YVYNNTERDN QGSKVTEFFD EWETMYHEMI WQRKLQDRKW LSWCAFRLPL WTRLSFHFAF2400
 2401 IVNALVARYY PLPEHSNSSI SLGNLYSWFA VFSSFLLAHY LRHDKIYLHK TSLLILASLC2460
 2461 FLLLSSIGVT LTLYIFGILQ LVNKIVHVVA FVSNKGLEDR PIAEILACRN LHYLLVYLFI2520
 2521 CILGLLVHPM IYCILLFDII FTEETLQNVI ASVTRNYQSI VWTGLLALIL LYFFSILGFL2580
 2581 YFRHDFYLEV DPVENDSSAT ISSGIPSETC PSEGCPGLQP SEKDDNDDEK KVKSCETLWM2640
 2641 CILQTGYQGL RNGGGIGDVL RNPAPWEDMF IWRVAYDMTF FVVLIVIVLN LIFGVIIDTF2700
 2701 GDLRAEKNEK EQILKNNCFI CGLDRSRFDN RSVTFETHRE TEHNIWHYLY YIVMLQIKDE2760
 2761 TEFTGPESYV AQCVKDRNLD WFPRMQALSL QDSELDTDQS EVKQMKDQLL QMMTLMREII2820
 2821 SQNEESRAFM EQFQPR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: itr-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: