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Protein Overview: nhr-2

General Information:
Name(s) found: nhr-2 / CE39002 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00003601 locus:nhr-2 Nuclear hormone receptor family member nhr-2 status:Confirmed UniProt:Q10902 protein_id:CCD61911.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 472 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPMNPELMH YPNQPHMMPG YPMINAYQQS YLQNPAQWTP EMLLCMQMQM QQMVPGTATN  60
   61 STYMPPQSKN TVTPNATSPL SQISDRDSGN DTISPPLTSQ NSATTPNYHN QPQMQLTPLQ 120
  121 QAKPEKEEIS PYAINNILSS TQSSPDNGNE ADDKENSSVR RNTFPASSAS TKKPRGTPYD 180
  181 RTNTPMTVVP QMPQFAPDFS NYNLTMNAWS EFFKKDRCMV CGDNSTGYHY GVQSCEGCKG 240
  241 FFRRSVHKNI AYVCTKGENC TFSYENCAAN RGVRTRCQAC RFAKCLAVGM NRDNVRVNKE 300
  301 TDKDVKPSVA SPNFEMTSQV KELTAAFVAN MPCSTHLTSG THAIGAIKKF IESVPALSSL 360
  361 LPKDEKALEM SIQKVMSGIL AIRAAFTFDP ITFYSCENPV NLLRGGIRNT VFNDCEVALL 420
  421 SGIHILQIVN GGVAEIFTSY CQGLRHQLSQ THLQEIGLCD RLLMRLGPYL NQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..71] MSA 2.188995 View MSA. No confident structure predictions are available.
    2 View Details [72..213] FFAS03 0.996 No description for 2j63A was found.
    3 View Details [214..313] PSI-BLAST 25.69897 Crystal Structure of Vitmain D Receptor and 9-cis Retinoic Acid Receptor DNA-Binding Domains Bound to a DR3 Response Element
    4 View Details [314..472] PSI-BLAST 15.69897 Progesterone receptor


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle