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Protein Overview: gi|4139260

General Information:
Name(s) found: gi|4139260 [NCBI NR]
Description(s) found:
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  • gi|4139260|gb|AAD03739.1| 1-deoxy-D-xylulose 5-phosphate reductoisomerase [Plasmodium falciparum] [NCBI NR]
  • 1-deoxy-D-xylulose 5-phosphate reductoisomerase [Plasmodium falciparum 3D7]gi|23497715|gb|AAN37254.1| 1-deoxy-D-xylulose 5-phosphate reductoisomerase [Plasmodium falciparum 3D7]gi|4139260|gb|AAD03739.1| 1-deoxy-D-xylulose 5-phosphate reductoisomerase [P [nrdb_11152004_Chlamydomonas]
  • 1-deoxy-D-xylulose 5-phosphate reductoisomerase [Plasmodium falciparum] [nr-271106-contam.fasta]
    • Organism: Plasmodium falciparum
    Length: 488 amino acids

    Gene Ontology:
    Cellular Component: apicoplast [IDALink to PubMed article]
    Biological Process: isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway [ISS]
    Molecular Function: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKYIYIYFF FITITINDLV INNTSKCVSI ERRKNNAYIN YGIGYNGPDN KITKSRRCKR  60
   61 IKLCKKDLID IGAIKKPINV AIFGSTGSIG TNALNIIREC NKIENVFNVK ALYVNKSVNE 120
  121 LYEQAREFLP EYLCIHDKSV YEELKELVKN IKDYKPIILC GDEGMKEICS SNSIDKIVIG 180
  181 IDSFQGLYST MYAIMNNKIV ALANKESIVS AGFFLKKLLN IHKNAKIIPV DSEHSAIFQC 240
  241 LDNNKVLKTK CLQDNFSKIN NINKIFLCSS GGPFQNLTMD ELKNVTSENA LKHPKWKMGK 300
  301 KITIDSATMM NKGLEVIETH FLFDVDYNDI EVIVHKECII HSCVEFIDKS VISQMYYPDM 360
  361 QIPILYSLTW PDRIKTNLKP LDLAQVSTLT FHKPSLEHFP CIKLAYQAGI KGNFYPTVLN 420
  421 ASNEIANNLF LNNKIKYFDI SSIISQVLES FNSQKVSENS EDLMKQILQI HSWAKDKATD 480
  481 IYNKHNSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..488] PSI-BLAST 167.0 No description for 2eghA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
    		•  3.73695658845135 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.60548927745815 bayes_pls_golite062009
  • catalytic activity
    		•  2.54843319568228 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase activity
    		•  2.42852631499395 bayes_pls_golite062009
  • glucose-6-phosphate dehydrogenase activity
    		•  2.40527964325542 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  1.41676087939212 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity
    		•  1.08771562641109 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.07588236908906 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  0.841370849960815 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle