YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|4139260
Organism:	Plasmodium falciparum
Length:	488 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|4139260.

Description	E-value	Query Range	Subject Range
gi\|17225989 - gi\|17225989\|gb\|AAL37560.1\|AF367205_1 1-deoxy-D-xylulose 5-phosphate reductoisomerase precursor [Oryz...	618.0	[0..77]	[488..76]
DXR_ORYSA - 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplast precursor (EC 1.1.1.267) (DXP reductois... DXR_ORYSJ - 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic OS=Oryza sativa subsp. japonica GN=DX...	617.0	[0..77]	[488..76]
gi\|34996397 - gi\|34996397\|emb\|CAE47438.1\| putative 1-deoxy-D-xylulose 5-phosphate reductoisomerase [Hordeum vulgar...	614.0	[0..77]	[481..86]
gi\|195622364, gi... - gi\|9801280\|emb\|CAC03581.1\| putative 1-deoxy-D-xylulose 5-phosphate reductoisomerase [Zea mays], gi\|1...	613.0	[0..77]	[488..75]
DXR_ARATH - 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic OS=Arabidopsis thaliana GN=DXR PE=2 S...	613.0	[0..77]	[481..80]
gi\|9800656 - gi\|9800656\|gb\|AAD56391.2\|AF182287_1 1-deoxy-D-xylulose-5-phosphate reductoisomerase [Artemisia annua...	612.0	[0..75]	[481..72]
gi\|91241600, gi\|... - gi\|94421688\|gb\|ABF18928.1\| putative 1-deoxy-D-xylulose 5-phosphate reductoisomerase [Hevea brasilien...	612.0	[0..77]	[488..74]
gi\|15679908 - gi\|15679908\|gb\|AAK96063.2\|AF331705_1 1-deoxy-D-xylulose-5-phosphate reductoisomerase [Lycopersicon e...	611.0	[0..77]	[488..78]
gi\|87299431 - gi\|87299431\|dbj\|BAE79548.1\| 1-deoxyxylulose 5-phosphate reductoisomerase [Chrysanthemum x morifolium...	611.0	[0..75]	[481..72]

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Predicted Domain #1

Region A:
Residues: [1-488]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKYIYIYFF FITITINDLV INNTSKCVSI ERRKNNAYIN YGIGYNGPDN KITKSRRCKR  60
   61 IKLCKKDLID IGAIKKPINV AIFGSTGSIG TNALNIIREC NKIENVFNVK ALYVNKSVNE 120
  121 LYEQAREFLP EYLCIHDKSV YEELKELVKN IKDYKPIILC GDEGMKEICS SNSIDKIVIG 180
  181 IDSFQGLYST MYAIMNNKIV ALANKESIVS AGFFLKKLLN IHKNAKIIPV DSEHSAIFQC 240
  241 LDNNKVLKTK CLQDNFSKIN NINKIFLCSS GGPFQNLTMD ELKNVTSENA LKHPKWKMGK 300
  301 KITIDSATMM NKGLEVIETH FLFDVDYNDI EVIVHKECII HSCVEFIDKS VISQMYYPDM 360
  361 QIPILYSLTW PDRIKTNLKP LDLAQVSTLT FHKPSLEHFP CIKLAYQAGI KGNFYPTVLN 420
  421 ASNEIANNLF LNNKIKYFDI SSIISQVLES FNSQKVSENS EDLMKQILQI HSWAKDKATD 480
  481 IYNKHNSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	167.0
Match:	2eghA
Description:	No description for 2eghA was found.

Predicted functions:

Term	Confidence	Notes
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	3.73695658845135	bayes_pls_golite062009
oxidoreductase activity	2.60548927745815	bayes_pls_golite062009
catalytic activity	2.54843319568228	bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase activity	2.42852631499395	bayes_pls_golite062009
glucose-6-phosphate dehydrogenase activity	2.40527964325542	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.41676087939212	bayes_pls_golite062009
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity	1.08771562641109	bayes_pls_golite062009
retinol dehydrogenase activity	1.07588236908906	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.841370849960815	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: