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Protein Overview: gi|20502828

General Information:
Name(s) found: gi|20502828 [NCBI NR]
Description(s) found:
Found 3 descriptions.
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  • gi|20502828|gb|AAM22644.1|AF465544_1 cGMP-dependent protein kinase [Plasmodium falciparum] [NCBI NR]
    • Organism: Plasmodium falciparum
    Length: 853 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: cGMP-dependent protein kinase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEDDNLKKG NERNKKKAIF SNDDFTGEDS LMEDHLELRE KLSEDIDMIK TSLKNNLVCS  60
   61 TLNDNEILTL SNYMQFFVFK SGNLVIKQGE KGSYFFIINS GKFDVYVNDK KVKTMGKGSS 120
  121 FGEAALIHNT QRSATIIAET DGTLWGVQRS TFRATLKQLS NRNFNENRTF IDSVSVFDML 180
  181 TEAQKNMITN ACVIQNFKSG ETIVKQGDYG DVLYILKEGK ATVYINDEEI RVLEKGSYFG 240
  241 ERALLYDEPR SATIIAKEPT ACASICRKLL NIVLGNLQVV LFRNIMTEAL QQSEIFKQFS 300
  301 GDQLNDLADT AIVRDYPANY NILHKDKVKS VKYIIVLEGK VELFLDDTSI GILSRGMSFG 360
  361 DQYVLNQKQP FKHTIKSLEV CKIALITETC LADCLGNNNI DASIDYNNKK SIIKKMYIFR 420
  421 YLTDKQCNLL IEAFRTTRYE EGDYIIQEGE VGSRFYIIKN GEVEIVKNKK RLRTLGKNDY 480
  481 FGERALLYDE PRTASVISKV NNVECWFVDK SVFLQIIQGP MLAHLEERIK MQDTKVEMDE 540
  541 LETERIIGRG TFGTVKLVHH KPTKIRYALK CVSKRSIINL NQQNNIKLER EITAENDHPF 600
  601 IIRLVRTFKD SKYFYFLTEL VTGGELYDAI RKLGLLSKSQ AQFYLGSIIL AIEYLHERNI 660
  661 VYRDLKPENI LLDKQGYVKL IDFGCAKKVQ GRAYTLVGTP HYMAPEVILG KGYGCTVDIW 720
  721 ALGICLYEFI CGPLPFGNDE EDQLEIFRDI LTGQLTFPDY VTDTDSINLM KRLLCRLPQG 780
  781 RIGCSINGFK DIKDHPFFSN FNWDKLAGRL LDPPLVSKSE TYAEDIDIKQ IEEEDAEDDE 840
  841 EPLNDEDNWD IDF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..299] PSI-BLAST 82.39794 REGULATORY SUBUNIT OF CAMP DEPENDENT PROTEIN KINASE
    2 View Details [300..539] PSI-BLAST 9.221849 p56-lck tyrosine kinase, SH3 domain; p56-lck tyrosine kinase
    3 View Details [540..775] PSI-BLAST 66.522879 No description for 2fh9A was found.
    4 View Details [776..853] FFAS03 2.45 cAMP-dependent PK, catalytic subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • cytoskeletal protein binding
    		•  4.41722924924158 bayes_pls_golite062009
  • actin binding
    		•  3.91045208670052 bayes_pls_golite062009
  • binding
    		•  3.12724619324809 bayes_pls_golite062009
  • actin filament binding
    		•  2.72908433443928 bayes_pls_golite062009
  • protein binding
    		•  2.14586566310919 bayes_pls_golite062009
  • insulin receptor binding
    		•  2.1238568876176 bayes_pls_golite062009
  • protein kinase activity
    		•  1.4654611643382 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.39494498759145 bayes_pls_golite062009
  • molecular adaptor activity
    		•  1.33740973673697 bayes_pls_golite062009
  • kinase activity
    		•  1.31102709888086 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.27380124084989 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  1.2323381312171 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.999269271132931 bayes_pls_golite062009
  • signal transducer activity
    		•  0.999269271132931 bayes_pls_golite062009
  • structural molecule activity
    		•  0.989403012920596 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
    		•  0.950445630788802 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.83823250804321 bayes_pls_golite062009
  • protein complex binding
    		•  0.76378777571169 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.540818657754841 bayes_pls_golite062009
  • structural constituent of muscle
    		•  0.52430033936893 bayes_pls_golite062009
  • transferase activity
    		•  0.4880159130787 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.476094076158571 bayes_pls_golite062009
  • transporter activity
    		•  0.373683990992143 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.371928447183203 bayes_pls_golite062009
  • DNA binding
    		•  0.281643350069021 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.151158240426264 bayes_pls_golite062009
  • kinase regulator activity
    		•  0.10704587503284 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle