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Protein Overview: gi|15828302

General Information:
Name(s) found: gi|15828302 [NCBI NR]
Description(s) found:
Found 3 descriptions.
SHOW ALL
  • gi|15828302|ref|NP_302565.1| uroporphyrin-III C-methyltransferase [Mycobacterium leprae TN] [NCBI NR]
    • Organism: Mycobacterium leprae TN
    Length: 563 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGATMTTRG RKLRPGRITF VGAGPGAPGL LTAQAVAVLA NAALVFIDPD VPEPVLALIG  60
   61 KDLPPVSGPA PAGPAAVTAG RAADGTLEGD HYQAAPMVMS GGADIRPALG DPTEVAKTLT 120
  121 AEARSGVDVV RLVAGDPLTV DAVIAEVNAV ARTNLQIEIV PGLVTSSVVP TYAGLPLGSS 180
  181 HTVADVRGDV DWEALAAAPG PLILQATASH LADAAHILID HGLDDATPCV VTAQGTTCQQ 240
  241 RSVETTLEGL ADSAVLVGTD TAGPLTGPLV VTIGKTVTSR ARLNWWESRA LYGWTVLVPR 300
  301 TKDQAGEMSE RLTSYGALPV EVPTIAVEPP RSPAQMERAV KGLVDGRFQW VVFTSTNAVR 360
  361 AVWEKFGEFG LDARAFSGVK IACVGEATAD RVRAFGISPE LVPAGEQSSL GLLDEFPPYD 420
  421 SVFDPVNRVL LPRADIATET LAEGLRGCGW EIEDVTAYRT VRAAPPPAAT REMIKTGGFD 480
  481 AVCFTSSSTV RNLVGIAGKP HARTVIACIG PKTAETASEF GLRVDVQPET AAVGPLVDAL 540
  541 AEHVARLRAE GALPPPRKKS RRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] PSI-BLAST 55.69897 Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
    2 View Details [289..563] PSI-BLAST 40.221849 Uroporphyrinogen III synthase (U3S, HemD)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uroporphyrin-III C-methyltransferase activity
    		•  3.70810184740502 bayes_pls_golite062009
  • C-methyltransferase activity
    		•  3.49766011792986 bayes_pls_golite062009
  • precorrin-2 dehydrogenase activity
    		•  2.67806035597297 bayes_pls_golite062009
  • sirohydrochlorin ferrochelatase activity
    		•  2.40719502419427 bayes_pls_golite062009
  • catalytic activity
    		•  1.85393572319476 bayes_pls_golite062009
  • transferase activity
    		•  1.11319893632325 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.934144410066549 bayes_pls_golite062009
  • precorrin-4 C11-methyltransferase activity
    		•  0.920471789208861 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.915475179027344 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.637525028271766 bayes_pls_golite062009
  • ferrochelatase activity
    		•  0.15375007777431 bayes_pls_golite062009
    2
    Term Confidence Notes
  • uroporphyrinogen-III synthase activity
    		•  3.19339392327514 bayes_pls_golite062009
  • catalytic activity
    		•  1.50868196926865 bayes_pls_golite062009
  • hydro-lyase activity
    		•  0.850411184249311 bayes_pls_golite062009
  • lyase activity
    		•  0.0536528882085157 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle