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Catalysis of the breakage of a carbon-oxygen bond. Catalysis of the cleavage of a carbon-oxygen bond by elimination of water. Catalysis of the reaction: hydroxymethylbilane = uroporphyrinogen-III + H2O.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: uroporphyrinogen-III synthase activity
Acc: GO:0004852
Aspect: Molecular Function
Desc: Catalysis of the reaction: hydroxymethylbilane = uroporphyrinogen-III + H2O.
Synonyms:
  • hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)
  • uroporphyrinogen isomerase activity
  • uroporphyrinogen III cosynthase activity
  • URO-synthase activity
  • uroporphyrinogen-III cosynthetase activity
  • hydroxymethylbilane hydro-lyase (cyclizing) activity
  • uroporphyrinogen-III cosynthase activity
  • porphobilinogenase activity
Proteins in PDR annotated with:
   This term: 21 [Search]
   Term or descendants: 21 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004852 - uroporphyrinogen-III synthase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle