Protein Overview: tlk-PI, FBpp0305...

General Information:
Name(s) found:	FBpp0311479 [FlyBase] FBpp0305895 [FlyBase] tlk-PI / FBpp0288858 [FlyBase]
Description(s) found: Found 27 descriptions. SHOW ALL	type=protein; loc=X:join(3675688..3677592,3677710..3678474,3678561..3678739,3679065..3679257,3679323..3679528,3679627..3679846,3680177..3680437); ID=FBpp0311479; name=tlk-PN; parent=FBgn0086899,FBtr0345319; dbxref=FlyBase:FBpp0311479,FlyBase_Annotation_IDs:CG34412-PN; MD5=76c29ed6d881d6289af25703e3c4c3d7; length=1242; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=X:join(3675688..3677592,3677710..3678474,3678561..3678739,3679065..3679257,3679323..3679528,3679627..3679846,3680177..3680437); ID=FBpp0305895; name=tlk-PM; parent=FBgn0086899,FBtr0333753; dbxref=REFSEQ:NP_001259222,GB_protein:AGB95068,FlyBase:FBpp0305895,FlyBase_Annotation_IDs:CG34412-PM; MD5=76c29ed6d881d6289af25703e3c4c3d7; length=1242; release=r5.56; species=Dmel; [FlyBase] The gene Tousled-like kinase is referred to in FlyBase by the symbol Dmel\tlk (CG34412, FBgn0086899). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:3614054..3682010. It has the cytological map location 3F1-3E7. There is experimental evidence that it has the molecular function</span>: protein binding; protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; protein amino acid autophosphorylation; mitotic cell cycle, embryonic; chromatin organization; protein amino acid phosphorylation; cell adhesion; histone phosphorylation; antimicrobial humoral response; regulation of cell cycle. 79 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; eye; macrochaeta; head. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1242 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	regulation of cell shape [IMP] protein amino acid autophosphorylation [IDA] histone phosphorylation [IMP] chromosome segregation [IGI] cell adhesion [IMP] regulation of cell cycle [IMP] antimicrobial humoral response [IMP] protein amino acid phosphorylation [IDA][ISS][NAS] chromatin organization [IGI] mitotic cell cycle, embryonic [IMP]
Molecular Function:	ATP binding [IEA] protein binding [IPI] protein kinase activity [IDA][NAS] protein serine/threonine kinase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPGAHLQMS PQNTSSLSQH HPHQQQQLQP PQQQQQHFPN HHSAQQQSQQ QQQQEQQNPQ  60
   61 QQAQQQQQIL PHQHLQHLHK HPHQLQLHQQ QQQQLHQQQQ QHFHQQSLQG LHQGSSNPDS 120
  121 NMSTGSSHSE KDVNDMLSGG AATPGAAAAA IQQQHPAFAP TLGMQQPPPP PPQHSNNGGE 180
  181 MGYLSAGTTT TTSVLTVGKP RTPAERKRKR KMPPCATSAD EAGSGGGSGG AGATVVNNSS 240
  241 LKGKSLAFRD MPKVNMSLNL GDRLGGSAGS GVGAGGAGSG GGGAGSGSGS GGGKSARLML 300
  301 PVSDNKKIND YFNKQQTGVG VGVPGGAGGN TAGLRGSHTG GGSKSPSSAQ QQQTAAQQQG 360
  361 SGVATGGSAG GSAGNQVQVQ TSSAYALYPP ASPQTQTSQQ QQQQQPGSDF HYVNSSKAQQ 420
  421 QQQRQQQQTS NQMVPPHVVV GLGGHPLSLA SIQQQTPLSQ QQQQQQQQQQ QQQLGPPTTS 480
  481 TASVVPTHPH QLGSLGVVGM VGVGVGVGVG VNVGVGPPLP PPPPMAMPAA IITYSKATQT 540
  541 EVSLHELQER EAEHESGKVK LDEMTRLSDE QKSQIVGNQK TIDQHKCHIA KCIDVVKKLL 600
  601 KEKSSIEKKE ARQKCMQNRL RLGQFVTQRV GATFQENWTD GYAFQELSRR QEEITAEREE 660
  661 IDRQKKQLMK KRPAESGRKR NNNSNQNNQQ QQQQQHQQQQ QQQNSNSNDS TQLTSGVVTG 720
  721 PGSDRVSVSV DSGLGGNNAG AIGGGTVGGG VGGGGVGGGG VGGGGGRGLS RSNSTQANQA 780
  781 QLLHNGGGGS GGNVGNSGGV GDRLSDRGGG GGGIGGNDSG SCSDSGTFLK PDPVSGAYTA 840
  841 QEYYEYDEIL KLRQNALKKE DADLQLEMEK LERERNLHIR ELKRILNEDQ SRFNNHPVLN 900
  901 DRYLLLMLLG KGGFSEVHKA FDLKEQRYVA CKVHQLNKDW KEDKKANYIK HALREYNIHK 960
  961 ALDHPRVVKL YDVFEIDANS FCTVLEYCDG HDLDFYLKQH KTIPEREARS IIMQVVSALK1020
 1021 YLNEIKPPVI HYDLKPGNIL LTEGNVCGEI KITDFGLSKV MDDENYNPDH GMDLTSQGAG1080
 1081 TYWYLPPECF VVGKNPPKIS SKVDVWSVGV IFYQCLYGKK PFGHNQSQAT ILEENTILKA1140
 1141 TEVQFSNKPT VSNEAKSFIR GCLAYRKEDR MDVFALARHE YIQPPIPKHG RGSLNQQQQA1200
 1201 QQQQQQQQQQ QQQQSSTSQA NSTGQTSFSA HMFGNMNQSS SS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.63

Protein Overview: tlk-PI, FBpp0305...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: