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Protein Overview: cat-2

General Information:
Name(s) found: cat-2 / CE37742 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00000296 locus:cat-2 status:Partially_confirmed UniProt:S6FWP9 protein_id:CDG24121.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 454 amino acids

    Gene Ontology:
    Cellular Component: axon [IDALink to PubMed article]
    Biological Process: response to food [IMPLink to PubMed articleLink to PubMed article]
    mechanosensory behavior [IMPLink to PubMed article]
    dopamine biosynthetic process [IMPLink to PubMed article]
    serotonin biosynthetic process [IEALink to PubMed article]
    dopamine metabolic process [ISSLink to PubMed article]
    habituation [IMPLink to PubMed article]
    aromatic amino acid family metabolic process [IEALink to PubMed article]
    L-phenylalanine catabolic process [IEALink to PubMed article]
    regulation of locomotion [IMPLink to PubMed article]
    catecholamine biosynthetic process [IEALink to PubMed article]
    Molecular Function: iron ion binding [IEALink to PubMed article]
    phenylalanine 4-monooxygenase activity [IEALink to PubMed article]
    monooxygenase activity [IEALink to PubMed article]
    tyrosine 3-monooxygenase activity [IEALink to PubMed article][ISSLink to PubMed article]
    tryptophan 5-monooxygenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRCQKILQQL NDEGIEVIFT ANDVTPIEFS IILTSTDPTL SNFVSDILQN MSSAKVQICH  60
   61 VETRGNEASH DVLLACKATK NQLIHSAELL TQNHVALTKF SIFAKKLSDE KNQSQIWFPR 120
  121 HISELDQCSK CITKYEPTTD PRHPGHGDVA YIARRKFLND QALEFKFGDE IGYVDYTEEE 180
  181 HATWKAVYEK LGDLHLSHTC AVYRQNLKIL QEEKVLTADR IPQIRDVNKF LQKKTGFELR 240
  241 PCSGLLSARD FLASLAFRVF QTTTYLRHHK SPHHSPEPDL IHELLGHVPM FSDPLLAQMS 300
  301 QDIGLMSLGA SDEHIEKLST VYWFIVEFGL CKEDGKLKAI GAGLLSAYGE LMHACSDAPE 360
  361 HKDFDPAVTA VQKYEDDDYQ PLYFVADSIH DALAKLRKYA SSMDRPFSVV YDPFTKSIEA 420
  421 IESSADLEKA FSRLSNDLSA ITHAADRMKI SITM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..454] PSI-BLAST 162.0 Phenylalanine hydroxylase N-terminal domain; Phenylalanine hydroxylase, PAH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
    		•  5.95179224585512 bayes_pls_golite062009
  • tyrosine 3-monooxygenase activity
    		•  5.29200621320545 bayes_pls_golite062009
  • phenylalanine 4-monooxygenase activity
    		•  5.13697132751033 bayes_pls_golite062009
  • acetolactate synthase activity
    		•  3.48670706716817 bayes_pls_golite062009
  • tryptophan 5-monooxygenase activity
    		•  3.21197226254744 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  2.5269324625528 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  2.3423688142986 bayes_pls_golite062009
  • monooxygenase activity
    		•  1.6613930139243 bayes_pls_golite062009
  • protein binding
    		•  1.5818067110205 bayes_pls_golite062009
  • binding
    		•  1.30541586472971 bayes_pls_golite062009
  • transferase activity
    		•  1.02290254973777 bayes_pls_golite062009
  • catalytic activity
    		•  0.932947046865376 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.699576439508937 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.124839138546463 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle