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Protein Overview: BRE1A_ARATH

General Information:
Name(s) found: BRE1A_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75303266|sp|Q8RXD6.1|BRE1A_ARATH RecName: Full=E3 ubiquitin-protein ligase BRE1-like 1; Short=AtBRE1; AltName: Full=Protein HISTONE MONOUBIQUITINATION 1; Short=AtHUB1 [NCBI NR]
  • gi|34098841|gb|AAQ56803.1| At2g44950 [Arabidopsis thaliana] [NCBI NR]
  • gi|30689877|ref|NP_182022.2| HUB1 (HISTONE MONO-UBIQUITINATION 1); protein binding / protein homodimerization/ ubiquitin-protein ligase/ zinc ion binding [Arabidopsis thaliana] [NCBI NR]
  • gi|19698951|gb|AAL91211.1| unknown protein [Arabidopsis thaliana] [NCBI NR]
  • E3 ubiquitin-protein ligase BRE1-like 1 OS=Arabidopsis thaliana GN=HUB1 PE=1 SV=1 [Swiss-Prot]
  • At2g44950 [Arabidopsis thaliana]gi|19698951|gb|AAL91211.1| unknown protein [Arabidopsis thaliana]gi|30689877|ref|NP_182022.2| zinc finger (C3HC4-type RING finger) family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Zinc finger (C3HC4-type RING finger) family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: HUB1 | HUB1 (HISTONE MONO-UBIQUITINATION 1); protein binding / ubiquitin-protein ligase/ zinc ion binding | chr2:18549677-18555322 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • unknown protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At2g44950 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • protein binding / ubiquitin-protein ligase/ zinc ion binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: RDO4, HUB1 | histone mono-ubiquitination 1 | chr2:18542602-18548247 REVERSE LENGTH=878 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 878 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    mitochondrion [IDA]
    Biological Process: cell division [IMP]
    defense response to fungus, incompatible interaction [IMP]
    seed dormancy [IMP]
    histone monoubiquitination [IMP]
    vegetative to reproductive phase transition of meristem [IMP]
    protein monoubiquitination [IDA]
    leaf morphogenesis [IMP]
    regulation of G2/M transition of mitotic cell cycle [IMP]
    cell growth [IMP]
    [NOT]regulation of timing of cell differentiation [IMP]
    histone H2B ubiquitination [IMP]
    Molecular Function: ubiquitin-protein ligase activity [IDA]
    zinc ion binding [ISS]
    protein binding [ISS]
    protein homodimerization activity [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTGEPDRK RRHFSSISPS EAAAAVKKQP FFWPSSEDKL DTAVLQFQNL KLSQKLEAQQ  60
   61 VECSILEDKL SQIKEKQLPY NSSLKTVHKS WEKLTASVES CSVRVSDSSS GAHRFVNKED 120
  121 GSSPAVKNDF INRLLETGAT ESSSSNICSN QMEENGVNTS SQMTQTLYNL VAATEDLRCL 180
  181 KDELYPTVLR TNLGKDLCGQ LALSELESEI KSFRGDLDDV LVKFKSLSRE LQSHRDADAK 240
  241 VRVDLKRIRG ELEDEVVELQ QCNGDLSALR AERDATAGAF FPVLSLGNKL ATSDRERDKQ 300
  301 RDLQDMETVL KELTVLASGR LQQLKNLHEE RTKMLGKMSN LQNKSKSVRC ISSSQACLSL 360
  361 KDQLEKSKEA VFQYMALLEK LQVEKDSIVW KEREINIKNE LGDVSRKTSA VTDSRMASLD 420
  421 SEIQKQLDEK MRIKTRLGNI SRERGRKEIF ADMKALISSF PEEMSSMRSQ LNNYKETAGG 480
  481 IHSLRADVQS LSGVLCRKTK EYEALQLRSA DYASQLGDLN ATVCDLKNSH EELKLFLDMY 540
  541 KRESTDARDI AEAKEQEYRA WAHVQSLKSS LDEQNLELRV KAANEAEAVS QQMLAAAEAE 600
  601 IADLRQKMDD CKRDVAKHSD ILKSKHEEHG TYLSEIQTIG SAYEDIVPQN QQLLLQVTER 660
  661 DDYNIKLFLE GITSRQMQDT LLIDKYIMDK DIQQGSAYAS FLSKKSSRIE DQLRFCTDQF 720
  721 QKLAEDKYQK SVSLENLQKK RADIGNGLEQ ARSRLEESHS KVEQSRLDYG ALELELEIER 780
  781 FNRRRIEEEM EIAKKKVSRL RSLIEGSSAI QKLRQELSEF KEILKCKACN DRPKEVVITK 840
  841 CYHLFCNPCV QKLTGTRQKK CPTCSASFGP NDIKPIYI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..276] PSI-BLAST 21.522879 Heavy meromyosin subfragment
    2 View Details [277..485] deduced N/A No confident structure predictions are available.
    3 View Details [486..878] PSI-BLAST 12.39794 Tropomyosin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle