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Protein Overview: BRCA1_ARATH

General Information:
Name(s) found: BRCA1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|79480107|ref|NP_193839.4| ATBRCA1; ubiquitin-protein ligase [Arabidopsis thaliana] [NCBI NR]
  • gi|75158839|sp|Q8RXD4.1|BRCA1_ARATH RecName: Full=Protein BREAST CANCER SUSCEPTIBILITY 1 homolog; Short=AtBRCA1 [NCBI NR]
  • gi|34365717|gb|AAQ65170.1| At4g21070 [Arabidopsis thaliana] [NCBI NR]
  • gi|28372474|gb|AAO39850.1| BRCA1 [Arabidopsis thaliana] [NCBI NR]
  • gi|19698963|gb|AAL91217.1| unknown protein [Arabidopsis thaliana] [NCBI NR]
  • Protein BREAST CANCER SUSCEPTIBILITY 1 homolog OS=Arabidopsis thaliana GN=BRCA1 PE=1 SV=1 [Swiss-Prot]
  • At4g21070 [Arabidopsis thaliana]gi|28372474|gb|AAO39850.1| BRCA1 [Arabidopsis thaliana]gi|19698963|gb|AAL91217.1| unknown protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Similar to zinc finger (C3HC4-type RING finger) family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATBRCA1 | ATBRCA1 (BREAST CANCER SUSCEPTIBILITY1); ubiquitin-protein ligase | chr4:11248185-11252644 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • At4g21070 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • unknown protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • BRCA1 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATBRCA1; ubiquitin-protein ligase/ zinc ion binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATBRCA1; ubiquitin-protein ligase [Arabidopsis thaliana] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • | Symbols: ATBRCA1, BRCA1 | breast cancer susceptibility1 | chr4:11248174-11252633 FORWARD LENGTH=941 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Protein BREAST CANCER SUSCEPTIBILITY 1 homolog OS=Arabidopsis thaliana GN=BRCA1 PE=2 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 941 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    intracellular [IEA]
    Biological Process: DNA repair [IMP]
    response to gamma radiation [IEP]
    Molecular Function: ubiquitin-protein ligase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADTSHLERM GRELKCPICL SLYNSAVSLS CNHVFCNACI VKSMKMDATC PVCKIPYHRR  60
   61 EIRGAPHMDS LVSIYKNMED ASGIKLFVSQ NNPSPSDKEK QVRDASVEKA SDKNRQGSRK 120
  121 GRASKRNEYG KTKEIDVDAP GPIVMKPSSQ TKKRVQLLQN LSAESLTKPT ESVETAEKPK 180
  181 DYTENTVIRL DEHPSLNKEG NLSPFFWLRD EDDGENSSQR TESDQLLGTT PVNVPSFSDL 240
  241 MDSDHESPSK EDEQQKPNPG DMFDSEMFEW TQRPCSPEIL PSPVKAKVLG RDEIDLTQKK 300
  301 LPKVKVASSK CKNRKAGSAR NTVARRSIGV SQEDNMESSA AATISEQQDS RGTSGTIIRN 360
  361 DVNTDENVKA KRATRSKAQS TRVQSDLNVS NEADGKQGTK RKRSSIKSSP AHPIAGPNEL 420
  421 SLGTEIVGKG DQDQAHGPSD THPEKRSPTE KPSLKKRGRK SNASSSLKDL SGKTQKKTSE 480
  481 KKLKLDSHMI SSKATQPHGN GILTAGLNQG GDKQDSRNNR KSTVGKDDHT MQVIEKCSTI 540
  541 NKSSSGGSAH LRRCNGSLTK KFTCAFCQCS EDTEASGEMT HYYRGEPVSA DFNGGSKVIH 600
  601 VHKNCAEWAP NVYFNDLTIV NLDVELTRSR RISCSCCGLK GAALGCYNKS CKNSFHVTCA 660
  661 KLIPECRWDN VKFVMLCPLD ASIKLPCEEA NSKDRKCKRT PKEPLHSQPK QVSGKANIRE 720
  721 LHIKQFHGFS KKLVLSCSGL TVEEKTVIAE FAELSGVTIS KNWDSTVTHV IASINENGAC 780
  781 KRTLKFMMAI LEGKWILTID WIKACMKNTK YVSEEPYEIT MDVHGIREGP YLGRQRALKK 840
  841 KPKLFTGLKF YIMGDFELAY KGYLQDLIVA AGGTILRRRP VSSDDNEAST IVVFSVEPSK 900
  901 KKTLTQRRSD AEALAKSARA RAASSSWVLD SIAGCQILVL I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..81] PSI-BLAST 3.154902 No description for 2cklB was found.
    2 View Details [82..307] deduced N/A No confident structure predictions are available.
    3 View Details [308..409] deduced N/A No confident structure predictions are available.
    4 View Details [410..515] deduced N/A No confident structure predictions are available.
    5 View Details [516..714] MSA 1.401997 View MSA. No confident structure predictions are available.
    6 View Details [715..941] PSI-BLAST 37.39794 No description for 3cojX was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle