Protein Overview: TRFE_RAT

General Information:
Name(s) found:	TRFE_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|61556986\|ref\|NP_001013128.1\| transferrin [Rattus norvegicus] [NCBI NR] gi\|56540994\|gb\|AAH87021.1\| Transferrin [Rattus norvegicus] [NCBI NR] gi\|33187764\|gb\|AAP97736.1\| liver regeneration-related protein LRRG03 [Rattus norvegicus] [NCBI NR] gi\|149018746\|gb\|EDL77387.1\| rCG25416, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|122066515\|sp\|P12346.3\|TRFE_RAT RecName: Full=Serotransferrin; Short=Transferrin; AltName: Full=Siderophilin; AltName: Full=Beta-1 metal-binding globulin; AltName: Full=Liver regeneration-related protein LRRG03; Flags: Precursor [NCBI NR] Serotransferrin OS=Rattus norvegicus GN=Tf PE=1 SV=3 [Swiss-Prot] liver regeneration-related protein LRRG03 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Liver regeneration-related protein LRRG03 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Serotransferrin precursor (Transferrin) (Siderophilin) (Beta-1-metal-binding globulin) (Liver regeneration-related protein LRRG03) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transferrin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG25416, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Transferrin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tf Isoform 1 of Serotransferrin [rat-ipi-250309-contam.fasta] Isoform 1 of Serotransferrin OS=Rattus norvegicus GN=Tf [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	698 amino acids
Gene Ontology:
Cellular Component:	secretory granule [UNKNOWN] late endosome [UNKNOWN] extracellular region [UNKNOWN][IEA] endocytic vesicle [UNKNOWN] basement membrane [IDA] extracellular space [IDA] early endosome [UNKNOWN] basal plasma membrane [UNKNOWN] endosome [UNKNOWN] perinuclear region of cytoplasm [UNKNOWN] basal part of cell [UNKNOWN] coated pit [UNKNOWN] cytoplasmic membrane-bounded vesicle [UNKNOWN] recycling endosome [UNKNOWN] apical plasma membrane [UNKNOWN]
Biological Process:	cellular iron ion homeostasis [IEA][TAS] ion transport [IEA] response to hypoxia [IEP] ferric iron transport [IDA] iron ion transport [UNKNOWN][IEA][TAS] SMAD protein signal transduction [UNKNOWN] response to organic cyclic substance [IEP] acute-phase response [IEP] positive regulation of myelination [IDA]
Molecular Function:	protein binding [UNKNOWN] ferric iron binding [IDA][IEA] metal ion binding [IEA] ferric iron transmembrane transporter activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFAVGALLA CAALGLCLAV PDKTVKWCAV SEHENTKCIS FRDHMKTVLP ADGPRLACVK  60
   61 KTSYQDCIKA ISGGEADAIT LDGGWVYDAG LTPNNLKPVA AEFYGSLEHP QTHYLAVAVV 120
  121 KKGTDFQLNQ LQGKKSCHTG LGRSAGWIIP IGLLFCNLPE PRKPLEKAVA SFFSGSCVPC 180
  181 ADPVAFPQLC QLCPGCGCSP TQPFFGYVGA FKCLRDGGGD VAFVKHTTIF EVLPQKADRD 240
  241 QYELLCLDNT RKPVDQYEDC YLARIPSHAV VARNGDGKED LIWEILKVAQ EHFGKGKSKD 300
  301 FQLFGSPLGK DLLFKDSAFG LLRVPPRMDY RLYLGHSYVT AIRNQREGVC PEGSIDSAPV 360
  361 KWCALSHQER AKCDEWSVSS NGQIECESAE STEDCIDKIV NGEADAMSLD GGHAYIAGQC 420
  421 GLVPVMAENY DISSCTNPQS DVFPKGYYAV AVVKASDSSI NWNNLKGKKS CHTGVDRTAG 480
  481 WNIPMGLLFS RINHCKFDEF FSQGCAPGYK KNSTLCDLCI GPAKCAPNNR EGYNGYTGAF 540
  541 QCLVEKGDVA FVKHQTVLEN TNGKNTAAWA KDLKQEDFQL LCPDGTKKPV TEFATCHLAQ 600
  601 APNHVVVSRK EKAARVSTVL TAQKDLFWKG DKDCTGNFCL FRSSTKDLLF RDDTKCLTKL 660
  661 PEGTTYEEYL GAEYLQAVGN IRKCSTSRLL EACTFHKS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TRFE_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: