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Protein Overview: gi|30258971, gi|...

General Information:
Name(s) found: gi|30264326 [NCBI NR]
gi|30258971 [NCBI NR]
Description(s) found:
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  • gi|30264326|ref|NP_846703.1| 5-methyltetrahydrofolate--homocysteine methyltransferase [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30258971|gb|AAP28189.1| 5-methyltetrahydrofolate--homocysteine methyltransferase [Bacillus anthracis str. Ames] [NCBI NR]
  • 5-methyltetrahydrofolate--homocysteine methyltransferase [Bacillus anthracis str. Sterne]gi|47778299|ref|YP_021121.2| 5-methyltetrahydrofolate--homocysteine methyltransferase [Bacillus anthracis str. 'Ames Ancestor']gi|30264326|ref|NP_846703.1| 5-methyl [nrdb_11152004_Chlamydomonas]
  • 5-methyltetrahydrofolate--homocysteine methyltransferase [Bacillus anthracis str. Ames] [nr-271106-contam.fasta]
    • Organism: Bacillus anthracis str. Ames
    Length: 1132 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: methionine biosynthetic process [ISSLink to PubMed article]
    Molecular Function: methionine synthase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYCIEEKLQN NILLLDGAMG TMIQQEDLTA EDFGGEEYEG CNEYLVETRP DVILKIHKAY  60
   61 IEAGADIIET NTFGATNIVL SDYELSHLDE ELNEKAARLA KQAVKESGKE VYVAGAMGPT 120
  121 TKAISVTGGV TFEELIEAYT RQARGLLKGE VDVLLVETSQ DMRNMKAAYI GIQAAFDELK 180
  181 KIVPIMISGT IEPMGTTLAG QTIEAFYLSV EHMKPLSVGL NCATGPEFMR DHIRSLSDLS 240
  241 ECYISCYPNA GLPDEDGHYH ESPSSLAEKV KRFAEEGWVN IIGGCCGTTP EHIKAMKEAL 300
  301 ASLKPREHHE REGHGVSGLE ALQYDDSMRP LFVGERTNVI GSRKFKRLVA EGKFEEAAEV 360
  361 ARAQVKKNAH IIDICMADPD RDEIEDMENF LAEVTKVLKV PIMIDSTDEH VMERALTYIQ 420
  421 GKAVINSINL EDGEERFIKV TPLLQKYGAA IVVGTIDEDG MAVSAERKLE IAKRSYELLT 480
  481 TKYGIRPSDI IFDALVFPVG TGDEEYIGSA AATIEGIRLI KEALPECLTI LGVSNISFGL 540
  541 PPAGREVLNS VFLYHATKAG LDYAIVNTEK LERYASIPDE EKRLADALLF ETTQETLEEF 600
  601 TNFYRVAKKK DVVVQETLTL DERLANYIVE GTKQGLHEDL SLALTEGRKP LDIINGPLMT 660
  661 GMDEVGRLFN NNELIVAEVL QSAESMKAAV SYLEPHMESS DSAKKGKVLL ATVKGDVHDI 720
  721 GKNLVEIILA NNGYEIINLG INVRSDRIVQ EVQEKKPDII GLSGLLVKSA QQMVTTAEDL 780
  781 KAADIDIPIV VGGAALTRKF TDNRISPSYK GLVCYASDAM TGLDIINKLQ KEEEREKMKQ 840
  841 DKKERHLHIV TKEEKKIEIP AVIEPLPKSE VMVPDSTKRI VLRDVPALHL APFLNRQMLL 900
  901 GHHLGLKGSV KKLLKEGDKR AHELNDLIDE LLQEGQSWLK PKAVYQFFPA QSDGQNIVIY 960
  961 DPEDHTRVIE RFTFPRQGRA PYRTLGDYLR PIGDEMDYVA FLSVTVGEGV RGIAEEWKAK1020
 1021 GDYLRSHAIQ SLALELAEGL AEKTHMLIRD RWGIPDSPEL TMEERFRTKY RGIRVSFGYP1080
 1081 ACPELADQEK LFRLIHPEEI GISLTEGFMM EPEASVTAMV FSHPEARYFS VL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..601] PSI-BLAST 117.0 Cobalamin-dependent methionine synthase (MetH) from Thermotoga maritima (Oxidized, Monoclinic)
    2 View Details [602..1132] PSI-BLAST 180.0 Methionine synthase domain; Methionine synthase, C-terminal domain; Methionine synthase SAM-binding domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • dihydropteroate synthase activity
    		•  5.55484533231129 bayes_pls_golite062009
  • S-methyltransferase activity
    		•  3.53817178180686 bayes_pls_golite062009
  • methyltransferase activity
    		•  3.47355858135695 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  3.39246539615995 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.30536381024187 bayes_pls_golite062009
  • transferase activity
    		•  2.35234138809715 bayes_pls_golite062009
  • 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity
    		•  1.59882258515727 bayes_pls_golite062009
  • catalytic activity
    		•  1.41033217274476 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.09502814971491 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.775834109629976 bayes_pls_golite062009
  • binding
    		•  0.660910809839792 bayes_pls_golite062009
  • dihydroneopterin aldolase activity
    		•  0.570043482286316 bayes_pls_golite062009
  • protein binding
    		•  0.422094211438801 bayes_pls_golite062009
  • diphosphotransferase activity
    		•  0.246882532482481 bayes_pls_golite062009
  • methionine synthase activity
    		•  0.191040886553873 bayes_pls_golite062009
  • 5-methyltetrahydrofolate-dependent methyltransferase activity
    		•  0.191040886553873 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle