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Protein Overview: gi|30256791, gi|...

General Information:
Name(s) found: gi|30262165 [NCBI NR]
gi|30256791 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • gi|30262165|ref|NP_844542.1| bifunctional uroporphyrinogen-III methyltransferase/uroporphyrinogen-III synthase [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30256791|gb|AAP26028.1| uroporphyrin-III C-methyltransferase, putative [Bacillus anthracis str. Ames] [NCBI NR]
    • Organism: Bacillus anthracis str. Ames
    Length: 474 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cobalamin biosynthetic process [ISSLink to PubMed article]
    Molecular Function: uroporphyrin-III C-methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGYVYLVGA GPGDEGLITK KAIECLKRAD IVLYDRLLNP FFLSYTKQTC ELMYCGKMPK  60
   61 NHIMRQEMIN AHLLQFAQEG KIVVRLKGGD PSIFGRVGEE AETLAAANIP YEIVPGITSS 120
  121 TAASSYAGIP LTHRNYSNSV TLLTGHAKGS LTDHGKYNSS HNSDTIAYYM GIKNLPTICK 180
  181 NLRQAGKKED TPVAVIEWGT TGKQRVVTGT LSTIVSIVKN ENISNPSMTI VGDVVSLRDQ 240
  241 IAWKEHKPLH GKKVLFTSAT NKTSVMKQKL QEAGAEIYQI PTFKKEEYTL TLEQIIEIFN 300
  301 VNRLVFCSAE SVEILMQSCS KYKKDIRSLQ AELQHMNVAT QEKLMQYGLL SKEAKFSSDT 360
  361 TVYLGRNINR IAFIQEKIGA GSYMMTHKYT IDHRFDEVHS RMLSEFLWDS IVFEGRASID 420
  421 TFLAEVKRLG FLDIVTLPFS YTDVPTLRYA NKVGFHNIDH QLQETLMQKD MVRQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..250] PSI-BLAST 65.0 Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
    2 View Details [251..474] PSI-BLAST 30.39794 Uroporphyrinogen III synthase (U3S, HemD)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • uroporphyrin-III C-methyltransferase activity
    		•  3.573271502205 bayes_pls_golite062009
  • C-methyltransferase activity
    		•  3.35393353163232 bayes_pls_golite062009
  • precorrin-4 C11-methyltransferase activity
    		•  2.18371138649366 bayes_pls_golite062009
  • catalytic activity
    		•  1.48349578618275 bayes_pls_golite062009
  • transferase activity
    		•  0.912524944496351 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.431791521097299 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.424918406685891 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.28351517300952 bayes_pls_golite062009
  • uroporphyrinogen-III synthase activity
    		•  0.00871858903098705 bayes_pls_golite062009
    2
    Term Confidence Notes
  • uroporphyrinogen-III synthase activity
    		•  3.34629127241283 bayes_pls_golite062009
  • catalytic activity
    		•  1.13824203225664 bayes_pls_golite062009
  • lyase activity
    		•  0.352588988142348 bayes_pls_golite062009
  • hydro-lyase activity
    		•  0.290711782955013 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.212880565996123 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle