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Protein Overview: gi|30261997, gi|...

General Information:
Name(s) found: gi|30261997 [NCBI NR]
gi|30256623 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|30261997|ref|NP_844374.1| homoserine dehydrogenase [Bacillus anthracis str. Ames] [NCBI NR]
  • gi|30256623|gb|AAP25860.1| homoserine dehydrogenase [Bacillus anthracis str. Ames] [NCBI NR]
    • Organism: Bacillus anthracis str. Ames
    Length: 431 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: aspartate family amino acid biosynthetic process [ISSLink to PubMed article]
    Molecular Function: homoserine dehydrogenase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNVIHVGVL GLGTVGSGVV HILKEHYKKI ALDTGYEVKV KTVVVRDLEK ERDVCIDGIV  60
   61 VTCHVDEVLN DPNIDIVVEV MGGIEEAKQH IVKALRNKKH VVTANKDLMA VYGAELLQLA 120
  121 NDNDCDLCYE ASVAGGIPVL RGLTDGLASD QIEKIMGIVN GTTNYMLTKM SQKGWSYEEA 180
  181 LQEAQKLGFA ESDPTADVDG LDAARKVAIL ANLGFSMNVS LDDVQVRGIR KVEKEDLQMA 240
  241 EKLGFTMKLI GKAEKQGSAI HLSVEPTLLP SHHPLSNVNN EFNAVYVHGQ AVGEVMFYGP 300
  301 GAGKLPTGSA VVSDIISIVK NMNQVPKNKS VLKEPEPYEL QGDEEVVSKY FLRISLRDEP 360
  361 GMLQKITECF VNYSVSLKEV IQLPLNRELA EVVVVTHQTS KYQFERVLGA IEDVASEINS 420
  421 YYIIEEEKQY V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..345] PSI-BLAST 42.221849 Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline
    2 View Details [346..431] PSI-BLAST 23.0 Crystal structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from E. coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • aspartate-semialdehyde dehydrogenase activity
    		•  3.92511214237139 bayes_pls_golite062009
  • catalytic activity
    		•  2.91887313269429 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.86254373278283 bayes_pls_golite062009
  • dihydrodipicolinate reductase activity
    		•  1.71989205356835 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  1.19591951564949 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  1.07932840802619 bayes_pls_golite062009
  • ketol-acid reductoisomerase activity
    		•  0.57325534211306 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.23458869447046 bayes_pls_golite062009
  • N-acetyl-gamma-glutamyl-phosphate reductase activity
    		•  0.22364954992375 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.22262673350502 bayes_pls_golite062009
  • glyceraldehyde-3-phosphate dehydrogenase activity
    		•  0.0876163188309598 bayes_pls_golite062009
    2
    Term Confidence Notes
  • acetolactate synthase activity
    		•  5.6098771388969 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  4.76464602837385 bayes_pls_golite062009
  • catalytic activity
    		•  1.01569611874813 bayes_pls_golite062009
  • transferase activity
    		•  0.07375530569672 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle